62458-44-0

Basic information

• Product Name: Isocostic acid
• Synonyms: Isocostic acid
• CAS NO: 62458-44-0
• Molecular Formula: C15H22 O2
• Molecular Weight: 0
• Mol File: 62458-44-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Isocostic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Isocostic acid(62458-44-0)
• EPA Substance Registry System: Isocostic acid(62458-44-0)

Safety Data

• Hazardous Substances Data: 62458-44-0(Hazardous Substances Data)

Upstream product

• 4586-68-9 ilicic acid 
• 4586-68-9 4-hydroxy-11⁽¹³⁾-eudesmen-12-oic acid 
• 347377-92-8 germacra-1⁽¹⁰⁾,4,11⁽¹³⁾-trien-12-oic acid 
• 19291-93-1 1,4a-dimethyl-4,4a,5,6,-tetrahydronaphthalen-2(3H)-one 

Relevant articles and documents

Sesquiterpenes from Tessaria absinthioides

The sesquiterpenes tessaric acid, 2-deoxytessaric acid, ilicic acid, 3- oxo-4,11(13)-eudesmdien-12-oic acid and 3β,5α-dihydroxycostic acid have been isolated from the aerial parts of Tessaria absinthioides. The structure of a new eudesmane, 3β,5β-dihydroxicostic acid, was established by spectroscopic data.

Gastric cytoprotective activity of ilicic aldehyde: Structure-activity relationships

A series of sesquiterpene compounds possessing both eudesmane and eremophilane skeletons were tested as gastric cytoprotective agents on male Wistar rats. The presence of an α,β-unsaturated aldehyde on the C-7 side chain together with a hydroxyl group at C-4 is the requirement for the observed antiulcerogenic activity. In an attempt to establish new molecular structural requirements for this gastric cytoprotective activity, a structure-activity study was performed.

Brominative lactonization in eudesmanes

The interaction of ilicic acid 1 with bromine affords directly the bromolactone 3.