624729-66-4

Basic information

• Product Name: 8-Amino-1,2,3,4-tetrahydro-2-naphthol
• Synonyms: 8-Amino-1,2,3,4-tetrahydro-2-naphthol;4-tetrahydro-;8-aMino-1;8-aMino-1,2,3,4-tetrahydronaphthalen-2-ol
• CAS NO: 624729-66-4
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.22
• Mol File: 624729-66-4.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 347.1 °C at 760 mmHg
• Flash Point: 163.7 °C
• Appearance: /
• Density: 1.204
• Vapor Pressure: 2.07E-05mmHg at 25°C
• Refractive Index: 1.64
• PKA: 14.72±0.20(Predicted)
• CAS DataBase Reference: 8-Amino-1,2,3,4-tetrahydro-2-naphthol(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Amino-1,2,3,4-tetrahydro-2-naphthol(624729-66-4)
• EPA Substance Registry System: 8-Amino-1,2,3,4-tetrahydro-2-naphthol(624729-66-4)

Safety Data

• Hazardous Substances Data: 624729-66-4(Hazardous Substances Data)

Usage

General Description

8-Amino-1,2,3,4-tetrahydro-2-naphthol is a chemical compound with the molecular formula C10H13NO and a molar mass of 163.22 g/mol. It is commonly used as a reagent in organic synthesis and is also used in the production of various pharmaceuticals and agrochemicals. 8-Amino-1,2,3,4-tetrahydro-2-naphthol is an amino alcohol, which means it contains both an amino group and a hydroxyl group. It is a white to off-white solid at room temperature and is soluble in organic solvents such as ethanol and acetone. 8-Amino-1,2,3,4-tetrahydro-2-naphthol is a versatile chemical that is used in a variety of industrial and research applications.

InChI:InChI=1/C10H13NO/c11-10-3-1-2-7-4-5-8(12)6-9(7)10/h1-3,8,12H,4-6,11H2

Upstream product

• 444619-84-5 8-bromo-1,2,3,4-tetrahydronaphthalen-2-ol 
• 117294-21-0 8-bromo-2-tetralone 
• 624729-65-3 (7-ethoxy-5,8-dihydronaphthalen-1-yl)amine 
• 1254716-32-9 tert-butyl N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)carbamate 
• 624729-74-4 8-amino-3,4-dihydronaphthalen-2(1H)-one 
• 118-46-7 8-amino-2-naphthol 

Downstream Products

• 711016-23-8 2-(3-bromophenyl)-N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide 
• 711016-22-7 N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-4-iodobenzamide 
• 879609-17-3 8-({2-chloro-6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}amino)-1,2,3,4-tetrahydronaphthalen-2-ol 
• 711016-15-8 3',4'-difluoro-N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)biphenyl-4-carboxamide 
• 711015-38-2 N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-N'-(4'-methylbiphenyl-3-yl)urea 
• 711016-20-5 2-biphenyl-3-yl-N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide 
• 710954-91-9 N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-N'-[3-piperidin-1-yl-4-(trifluoromethyl)benzyl]urea 
• 1146695-97-7 8-{[5-(4-bromophenyl)-4-ethyl-1,3-oxazol-2-yl]amino}-1,2,3,4-tetrahydronaphthalen-2-ol 
• 1146695-94-4 8-({4-ethyl-5-[2-fluoro-4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl}amino)-1,2,3,4-tetrahydronaphthalen-2-ol 
• 1146695-91-1 8-({5-[3-chloro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-oxazol-2-yl}amino)-1,2,3,4-tetrahydronaphthalen-2-ol 
• 1146695-72-8 8-{[5-(4-chloro-3-fluorophenyl)-4-methyl-1,3-oxazol-2-yl]amino}-1,2,3,4-tetrahydronaphthalen-2-ol 
• 1146695-69-3 8-{[5-(4-cyclopropyl-3-fluorophenyl)-4-methyl-1,3-oxazol-2-yl]amino}-1,2,3,4-tetrahydronaphthalen-2-ol 
• 912957-55-2 8-(6-(2-Amino-4-(trifluoromethyl)phenyl)pyrimidin-4-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol 
• 913295-42-8 8-(6-(4-(Trifluoromethyl)phenyl)pyrimidin-4-ylamino)-1,2,3,4-tetrahydro-naphthalen-2-ol 

Relevant articles and documents

[heteroshikuridenasetoamido[heteroshikuridenasetoamido] derivative

The present invention provides, a novel method for producing a compound represented by formula (I) and a novel method for producing a compound represented by formula (B) or a salt thereof, which are intermediates in the production of formula (I).

Selective Catalytic Hydrogenation of Arenols by a Well-Defined Complex of Ruthenium and Phosphorus-Nitrogen PN3-Pincer Ligand Containing a Phenanthroline Backbone

Selective catalytic hydrogenation of aromatic compounds is extremely challenging using transition-metal catalysts. Hydrogenation of arenols to substituted tetrahydronaphthols or cyclohexanols has been reported only with heterogeneous catalysts. Herein, we demonstrate the selective hydrogenation of arenols to the corresponding tetrahydronaphthols or cyclohexanols catalyzed by a phenanthroline-based PN3-ruthenium pincer catalyst.

SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted aromatic carboxamide and urea derivatives, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions (formula (I)).