62501-72-8Relevant articles and documents
Palladium-Catalyzed Asymmetric Dihydroxylation of 1,3-Dienes with Catechols
Fan, Tao,Shen, Hong-Cheng,Han, Zhi-Yong,Gong, Liu-Zhu
, p. 226 - 232 (2019)
A palladium-catalyzed asymmetric dihydroxylation of 1,3-dienes with catechols is developed using chiral pyridinebis(oxazoline) ligands. Various chiral 2-substituted 1,4-benzodioxanes could be synthesized with moderate to high yields and enantioselectivities from readily available starting materials. The reaction is proposed to proceed through a cascade Wacker-type hydroxypalladation/asymmetric allylation process.
Synthesis of enantiomerically pure 7-hydroxy-2-substituted-2,3-dihydro-1,4-benzodioxin derivatives
Khouili,Lazar,Guillaumet,Coudert
, p. 535 - 536 (1994)
A rapid and simple procedure for the preparation of the two pure enantiomers of 7-hydroxy-2-substituted-2,3-dihydro-1,4-benzodioxin derivatives is described.
Preparation method of 1,4-benzdioxan-2-formic acid
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Paragraph 0060; 0066; 0067; 0068; 0096; 0110, (2018/07/30)
The invention provides a preparation method of 1,4-benzdioxan-2-formic acid. The preparation method comprises the following steps: by taking benzylodiglycidyl ether and o-halogen phenol as raw materials, performing cyclization reaction, debenzylation reaction and oxidization reaction to obtain the 1,4-benzdioxan-2-formic acid. The preparation method provided by the invention is simple in reactionprocess; as the benzylodiglycidyl ether and the o-halogen phenol are used as the raw materials for reaction, no pollutants are produced, and no-irritative and no-allergic objects are produced; compared with other existing lines, the preparation method is environmentally friendly, high in total yield and favorable for mass production; the ee value of the finally prepared 1,4-benzdioxan-2-formic acid is more than or equal to 99 percent, and the chiral purity is high.