62501-71-7

Basic information

• Product Name: 1,4-Benzodioxin, 2,3-dihydro-2-[(phenylmethoxy)methyl]-, (R)-
• CAS NO: 62501-71-7
• Molecular Formula: C16H16O3
• Molecular Weight: 256.301
• Mol File: 62501-71-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,4-Benzodioxin, 2,3-dihydro-2-[(phenylmethoxy)methyl]-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzodioxin, 2,3-dihydro-2-[(phenylmethoxy)methyl]-, (R)-(62501-71-7)
• EPA Substance Registry System: 1,4-Benzodioxin, 2,3-dihydro-2-[(phenylmethoxy)methyl]-, (R)-(62501-71-7)

Safety Data

• Hazardous Substances Data: 62501-71-7(Hazardous Substances Data)

Upstream product

• 120-80-9 benzene-1,2-diol 
• 164515-27-9 (2S)-1-(2'-benzyloxyphenoxy)-2-tosyloxy-3-benzyloxypropane 
• 56552-80-8 (R)-3-benzyloxy-1,2-propanediol 
• 16495-03-7 (S)-4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane 
• 164515-26-8 (2S)-1-(2'-benzyloxyphenoxy)-3-benzyloxy-2-propanol 
• 14618-80-5 (R)-benzyl glycidol 
• 100-44-7 benzyl chloride 

Downstream Products

• 98572-00-0 (S)-2-hydroxymethyl-1,4-benzodioxane 
• 70918-53-5 (+)-(2R)-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid 
• 1219800-50-6 (R)-tert-butyl 4-(2,3-dihydrobenzo[b][1,4]dioxine-2-carbonyl)piperazine-1-carboxylate 
• 860173-98-4 (R)-N-(1,4-benzodioxan-2-carbonyl)piperazine 
• 104874-86-4 (R)-doxazosin 
• 70918-54-6 (S)‐1,4‐benzodioxane‐2‐carboxylic acid 
• 1415584-44-9 (S)-N-Boc-(1,4-benzodioxan-2-carbonyl)piperazine 
• 401941-54-6 (S)-N-(1,4-benzodioxan-2-carbonyl)piperazine 
• 104874-86-4 (S)-doxazosin 
• 81602-24-6 (R)-WB-4101 
• 46049-48-3 (R)-2-((amino)methyl)-1,4-benzodioxane 
• 62501-73-9 (2S)-2-(hydroxymethyl)-1,4-benzodioxan tosylate 
• 62501-72-8 (R)-2-hydroxymethyl-1,4-benzodioxane 

Relevant articles and documents

Preparation method of 1,4-benzdioxan-2-formic acid

The invention provides a preparation method of 1,4-benzdioxan-2-formic acid. The preparation method comprises the following steps: by taking benzylodiglycidyl ether and o-halogen phenol as raw materials, performing cyclization reaction, debenzylation reaction and oxidization reaction to obtain the 1,4-benzdioxan-2-formic acid. The preparation method provided by the invention is simple in reactionprocess; as the benzylodiglycidyl ether and the o-halogen phenol are used as the raw materials for reaction, no pollutants are produced, and no-irritative and no-allergic objects are produced; compared with other existing lines, the preparation method is environmentally friendly, high in total yield and favorable for mass production; the ee value of the finally prepared 1,4-benzdioxan-2-formic acid is more than or equal to 99 percent, and the chiral purity is high.

Synthesis, binding affinities for α-adrenoceptor and eudismic analysis of chiral benzodioxane derivatives and their chiral opened analogues

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