6251-70-3 Usage
General Description
21-deoxytetrahydroaldosterone is a type of steroid hormone that is a precursor to aldosterone, which is responsible for regulating salt and water balance in the body. It is produced in the adrenal gland and plays a role in controlling blood pressure and maintaining electrolyte balance. 21-deoxytetrahydroaldosterone is synthesized from the precursor hormone, 11-deoxycorticosterone, and is converted into aldosterone through a series of enzymatic reactions. This chemical is important for the proper functioning of the renin-angiotensin-aldosterone system, which helps to regulate blood pressure and fluid balance in the body. Abnormal levels of 21-deoxytetrahydroaldosterone can lead to conditions such as hypertension and electrolyte imbalances. Overall, this chemical is crucial for the body's homeostasis and proper functioning.
Check Digit Verification of cas no
The CAS Registry Mumber 6251-70-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,5 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6251-70:
(6*6)+(5*2)+(4*5)+(3*1)+(2*7)+(1*0)=83
83 % 10 = 3
So 6251-70-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H32O4/c1-11(22)15-5-6-16-14-4-3-12-9-13(23)7-8-20(12,2)18(14)17-10-21(15,16)19(24)25-17/h12-19,23-24H,3-10H2,1-2H3/t12-,13-,14+,15-,16+,17-,18-,19?,20+,21?/m1/s1
6251-70-3Relevant academic research and scientific papers
18-Substituted Steroids. Part 5. Synthesis of 3α,18-Dihydroxy-11β,18-epoxy-5β-pregnan-20-one (21-Deoxy-3α,5β-tetrahydroaldosterone)
Crump, Douglas R.,Kirk, David N.,Miller, Barry W.
, p. 2597 - 2607 (2007/10/02)
21-Deoxy-3α,5β-tetrahydroaldosterone (5) has been prepared from 3α-acetoxy-20β-hydroxy-5β-pregnan-11-one (7) via the hypoiodite reaction sequence (lead tetra-acetate-iodine-hν; oxidation) followed by reduction and rearrangement of 18,20β-lactone-11-ketone