62532-99-4

Basic information

• Product Name: 2-THIEN-2-YLANILINE
• Synonyms: ART-CHEM-BB B025038;2-THIEN-2-YLANILINE;2-THIEN-2-YLANILINE HYDROCHLORIDE;2-THIOPHEN-2-YL-PHENYLAMINE;2-(2-THIENYL)ANILINE;2-(2-THIENYL)ANILINE HYDROCHLORIDE;AKOS B025038;AKOS BAR-0198
• CAS NO: 62532-99-4
• Molecular Formula: C₁₀H₉NS
• Molecular Weight: 175.25
• Mol File: 62532-99-4.mol

Chemical Properties

• Melting Point: 35-36 °C
• Boiling Point: 303.8 °C at 760 mmHg
• Flash Point: 137.5 °C
• Appearance: /
• Density: 1.196 g/cm³
• Vapor Pressure: 0.000911mmHg at 25°C
• Refractive Index: 1.65
• PKA: 2.96±0.10(Predicted)
• CAS DataBase Reference: 2-THIEN-2-YLANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-THIEN-2-YLANILINE(62532-99-4)
• EPA Substance Registry System: 2-THIEN-2-YLANILINE(62532-99-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 62532-99-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Thien-2-ylaniline is used as a key intermediate in the synthesis of pharmaceuticals for its potential anti-tumor and anti-inflammatory properties. Its unique structure allows for the development of new drugs that can target specific biological pathways, offering novel treatment options for various diseases.
Used in Organic Material Synthesis:
In the field of organic materials, 2-Thien-2-ylaniline is utilized as a building block for creating new compounds with tailored properties. Its reactivity and the presence of the thiophene ring contribute to the formation of materials with specific characteristics, such as improved stability or enhanced performance in various applications.
Used in Organic Electronics:
2-Thien-2-ylaniline is studied for its potential use as a light-emitting material in organic electronics. Its electronic properties and the ability to form stable films make it a promising candidate for applications in organic light-emitting diodes (OLEDs) and other electronic devices.
Used in Solar Cell Technology:
Additionally, 2-Thien-2-ylaniline has been investigated for its potential as a photovoltaic material in solar cells. Its light-absorbing properties and compatibility with other materials in solar cell structures suggest its use in improving the efficiency and performance of solar energy conversion devices.
Overall, 2-Thien-2-ylaniline's diverse range of uses and potential applications across various industries underscores its importance in the development of innovative materials and technologies.

InChI:InChI=1/C10H9NS/c11-9-5-2-1-4-8(9)10-6-3-7-12-10/h1-7H,11H2

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Downstream Products

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Relevant articles and documents

Electrochemical Palladium-Catalyzed Intramolecular C—H Amination of 2-Amidobiaryls for Synthesis of Carbazoles

The synthesis of carbazoles based on the electrochemical Pd-catalyzed intramolecular C—H amination of 2-amidobiaryls through oxidative cross coupling has been achieved under mild reaction conditions. The reaction can be carried out in undivided cell without the addition of external chemical oxidant. Besides good functional group compatibility, the desired carbazoles can be scaled up and modified easily. Compared with previous methods, this protocol affords a simple and sustainable avenue for the construction of carbazoles.

α-Bromoacrylic Acids as C1 Insertion Units for Palladium-Catalyzed Decarboxylative Synthesis of Diverse Dibenzofulvenes

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Cascade One-Pot Synthesis of Orange-Red-Fluorescent Polycyclic Cinnolino[2,3-f]phenanthridin-9-ium Salts by Palladium(II)-Catalyzed C?H Bond Activation of 2-Azobiaryl Compounds and Alkenes

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Self-Assembled Multilayer Iron(0) Nanoparticle Catalyst for Ligand-Free Carbon-Carbon/Carbon-Nitrogen Bond-Forming Reactions

Self-assembled multilayer iron(0) nanoparticles (NPs, 6-10 nm), namely, sulfur-modified Au-supported Fe(0) [SAFe(0)], were developed for ligand-free one-pot carbon-carbon/carbon-nitrogen bond-forming reactions. SAFe(0) was successfully prepared using a well-established metal-nanoparticle catalyst preparative protocol by simultaneous in situ metal NP and nanospace organization (PSSO) with 1,4-bis(trimethylsilyl)-1,4-dihydropyrazine (Si-DHP) as a strong reducing agent. SAFe(0) was easy to handle in air and could be recycled with a low iron-leaching rate in reaction cycles.

Effective bimetallic composite catalysts for the synthesis of arylated furans and thiophenes in aqueous media

[Figure not available: see fulltext.] N-(4,6-Dimethylpyrimidin-2-yl)-5-phenylisoxazole-3-carboxamide was used as a ligand for obtaining bimetallic boron-containing heterogeneous catalysts Pd–Ni(Co)–B–L (Ni(Co):Pd = 9:1). The obtained composites were highl

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Rhodium(I)-Catalyzed Aryl C-H Carboxylation of 2-Arylanilines with CO2

An unprecedented Rh(I)-catalyzed, amino-group-assisted C-H carboxylation of 2-arylanilines with CO2 under redox-neutral conditions has been developed. This reaction was promoted by a phosphine ligand with t-BuOK as the base and did not require the use of additional strong organometallic reagent. It enabled an efficient direct conversion of a broad range of 2-(hetero)arylanilines including electron-deficient heteroarenes to various phenanthridinones. Possible intermediates of the reaction were also evaluated in the preliminary mechanistic studies.

Metal- and additive-free cascade trifluoroethylation/cyclization of organic isoselenocyanates by phenyl(2,2,2-trifluoroethyl)iodonium triflate

A novel and convenient cascade trifluoroethylation/cyclization of organic isoselenocyanates by phenyl(2,2,2-trifluoroethyl)iodonium triflate is reported. A series of 2-isoselenocyanobiaryls and aryl alkyl isoselenocyanates reacted with phenyl(2,2,2-trifluoroethyl)iodonium triflate in CH2Cl2 at 40 °C under metal- and additive-free conditions for 3 h to provide the corresponding trifluoroethylselenolated phenanthridines and 3,4-dihydroisoquinoline derivatives in good to excellent yields. The reaction represents the first general approach to access trifluoroethylselenolated phenanthridines and 3,4-dihydroisoquinolines from organic isoselenocyanates.

FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2

The present invention relates to fluorophenyl substituted muscarinic receptor ligands with selectivity for M3 over M2 and to the use of these compounds in the treatment of various diseases such as asthma, chronic obstructive pulmonary disease (COPD), bronchopulmonary dysplasia (BPD) and urinary incontinence.

Cobalt(II)-Catalyzed [5+2] C?H Annulation of o-Arylanilines with Alkynes: An Expedient Route to Dibenzo-[b,d]azepines

The first example of CoCl2-catalyzed formal [5+2] oxidative annulation of o-arylanilines with alkynes was developed, giving access to various important imine-containing dibenzo-[b,d]azepine scaffolds through sequential C?C/C?N bond formation. The reaction employs catalytic amount of manganese and oxygen as cooxidants, and features a broad substrate scope. Preliminary mechanistic studies suggested that C?H activation is involved in the rate-determining step. Moreover, both internal and terminal alkynes are well tolerated in this transformation. Besides, a regioselective migratory insertion was observed when using terminal alkynes as substrates. (Figure presented.).