62574-23-6Relevant academic research and scientific papers
Soft-enolization Baker-Venkataraman Rearrangement Enabled Total Synthesis of Dirchromones and Related 2-Substituted Chromones
St-Gelais, Alexis,Alsarraf, Jér?me,Legault, Jean,Gauthier, Charles,Pichette, André
supporting information, p. 7424 - 7428 (2019/01/03)
A seven-step total synthesis of the original scaffold of cytotoxic dirchromones involving an unprecedented soft-enolization Baker-Venkataraman rearrangement was designed. The methodology enabled access to naturally occurring dirchromone 1 (21% overall yield) at gram-scale, which was screened for cytotoxicity against 13 cancer cell lines. The scope of the soft-enolization Baker-Venkataraman rearrangement encompasses diversely substituted dirchromones, including flavonoids, 2-styrylchromones, and 2-phenylethylchromones.
Chemical differentiation of three DMSP lyases from the marine: Roseobacter group
Burkhardt, Immo,Lauterbach, Lukas,Brock, Nelson L.,Dickschat, Jeroen S.
supporting information, p. 4432 - 4439 (2017/07/10)
Dimethylsulfoniopropionate (DMSP) catabolism of marine bacteria plays an important role in marine and global ecology. The genome of Ruegeria pomeroyi DSS-3, a model organism from the Roseobacter group, harbours no less than three genes for different DMSP lyases (DddW, DddP and DddQ) that catalyse the degradation of DMSP to dimethyl sulfide (DMS) and acrylate. Despite their apparent similar function these enzymes show no significant overall sequence identity. In this work DddQ and DddW from R. pomeroyi and the DddP homolog from Phaeobacter inhibens DSM 17395 were functionally characterised and their substrate scope was tested using several synthetic DMSP analogues. Comparative kinetic assays revealed differences in the conversion of DMSP and its analogues in terms of selectivity and overall velocity, giving additional insights into the molecular mechanisms of DMSP lyases and into their putatively different biological functions.
PESTICIDAL COMPOSITIONS
-
Paragraph 0176; 0177, (2013/03/26)
Molecules according to Formula One: and their uses are disclosed herein.
S,S-Dialkyl Dithiocarbonates as a Convenient Source of Alkanethiols: an Improved Synthesis of Alkylthiocarboxylic Acids
Cadamuro, Silvano,Degani, Iacopo,Fochi, Rita,Regondi, Valeria
, p. 1070 - 1074 (2007/10/02)
A wide variety of β-alkylthiocarboxylic acids are obtained by addition of alkanethiols - generated in situ from S,S-dialkyl dithiocarbonates - to appropriate α,β-unsaturated carboxylic acids in good to excellent yields.
CARBOXYACYL, MERCAPTO AND ACYLMERCAPTO DERIVATIVES OF HETEROBICYCLO COMPOUNDS
-
, (2008/06/13)
A compound of the formula STR1 wherein R 1 is hydrogen, lower alkyl, phenyl lower alkyl or halo substituted lower alkyl; R. sub.2 is hydrogen, lower alkyl, phenyl lower alkyl or halo substituted lower alkyl;n is 0, 1 or 2;X is--(CH 2)
