562-54-9

Basic information

• Product Name: Potassium methyl sulfate
• Synonyms: sulfuricacid,monomethylester,potassiumsalt;METHYL POTASSIUM SULFATE;METHYL SULFATE POTASSIUM SALT;METHYLSULFURIC ACID POTASSIUM SALT;POTASSIUM METHYL SULFATE;POTASSIUM METHYLSULFURATE;potassium methyl sulphate;Sulfuric acid methyl=potassium salt
• CAS NO: 562-54-9
• Molecular Formula: CH₃O₄S*K
• Molecular Weight: 150.2
• EINECS: 209-231-3
• Mol File: 562-54-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 212-217 °C
• Appearance: White/Crystals or Crystalline Powder
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: Methanol (Slightly), Water (Slightly)
• Water Solubility: Soluble
• CAS DataBase Reference: Potassium methyl sulfate(CAS DataBase Reference)
• NIST Chemistry Reference: Potassium methyl sulfate(562-54-9)
• EPA Substance Registry System: Potassium methyl sulfate(562-54-9)

Safety Data

• Hazard Codes: T
• Statements: 45-36/37/38-20/22
• Safety Statements: 53-45-36/37/39-26
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 562-54-9(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline powder

Uses

Methylsulfuric acid potassium salt (cas# 562-54-9) is used as a multifunctional printing and dyeing scouring agent.

InChI:InChI=1/CH4O4S.K/c1-5-6(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1

Synthetic route

dimethyl sulfate (77-78-1) → potassium methyl sulfate (562-54-9)

Conditions	Yield
With potassium acetate In methanol at 5 - 50℃; for 5.16h;	63%
With methanol; potassium hydroxide; water

benzoic acid methyl ester (93-58-3) → potassium methyl sulfate (562-54-9) + Potassium benzoate (582-25-2)

Conditions	Yield
With sulfur trioxide; water 1.) CH2Cl2, 22 deg C, 1150 min, 2.) 70-80 deg C, 30 min; Yield given. Multistep reaction. Yields of byproduct given;
With sulfur trioxide; water 1.) CH2Cl2, 22 deg C, 1150 min, 2.) 70-80 deg C, 30 min; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

benzoic acid methyl ester (93-58-3) → potassium methyl sulfate (562-54-9) + dipotassium 3-sulfobenzoate

Conditions	Yield
With sulfur trioxide; water 1.) CH2Cl2, 22 deg C, 1150 min, 2.) 70 - 80 deg C, 30 min; Multistep reaction. Title compound not separated from byproducts;

methyl 1-naphthoate (2459-24-7) → 5-sulfo-1-naphthoic acid (51307-69-8) + 8-sulfo-1-naphthoic acid + potassium methyl sulfate (562-54-9)

Conditions	Yield
With sulfur trioxide; water 1.) CH2Cl2, 22 deg C, 140 min, 2.) 70 - 80 deg C, 30 min; Multistep reaction. Title compound not separated from byproducts;

methyl naphthalene-2-carboxylate (2459-25-8) → naphthalene-2-acetic-8-sulphonic acid (739346-35-1) + 5-sulfo-2-naphthoic acid (738561-48-3) + potassium methyl sulfate (562-54-9)

Conditions	Yield
With sulfur trioxide; water 1.) CH2Cl2, 22 deg C, 120 min, 2.) 70 - 80 deg C, 30 min; Multistep reaction. Title compound not separated from byproducts;

methyl naphthalene-2-carboxylate (2459-25-8) → naphthalene-2-acetic-8-sulphonic acid (739346-35-1) + 5-sulfo-2-naphthoic acid (738561-48-3) + potassium methyl sulfate (562-54-9) + 4,8-disulfo-2-naphthoic acid + 7,7-disulfo-2-naphthoic acid

Conditions	Yield
With sulfur trioxide; water Product distribution; multistep reaction; various reaction conditions;

methyl naphthalene-2-carboxylate (2459-25-8) → naphthalene-2-acetic-8-sulphonic acid (739346-35-1) + potassium methyl sulfate (562-54-9) + 4,8-disulfo-2-naphthoic acid + 7,7-disulfo-2-naphthoic acid

Conditions	Yield
With sulfur trioxide; water 1.) CH2Cl2, 22 deg C, 1530 min, 2.) 70 - 80 deg C, 30 min; Multistep reaction. Title compound not separated from byproducts;

water (7732-18-5) + dimethyl sulfate (77-78-1) + methanolic KOH-solution → potassium methyl sulfate (562-54-9)

sulfuric acid monomethyl ester; dichloro tin (IV)-compound + aqueous KOH-solution → potassium methyl sulfate (562-54-9) + Sn(OH)4 + KCl

piperazine (110-85-0) + potassium methyl sulfate (562-54-9) → N,N'-dimethylpiperazine (106-58-1)

Conditions	Yield
With water

acetamide (60-35-5) + potassium methyl sulfate (562-54-9) → N-methyl-acetamide (79-16-3)

Conditions	Yield
With sodium ethanolate

benzoimidazole (51-17-2) + potassium methyl sulfate (562-54-9) → 1-Methylbenzimidazole (1632-83-3)

Conditions	Yield
With sodium hydroxide

3,4-Dimethylphenol (95-65-8) + potassium methyl sulfate (562-54-9) → 3,4-dimethylanisole (4685-47-6)

Conditions	Yield
With sodium hydroxide

4,5,6,7-tetrahydro-1H-benzimidazole (3752-24-7) + potassium methyl sulfate (562-54-9) → 1-methyl-4,5,6,7-tetrahydro-1H-benzo[d]imidazole (1837-49-6)

Conditions	Yield
With sodium hydroxide

N-ethylisobutylamine (13205-60-2) + potassium methyl sulfate (562-54-9) → ethyl-isobutyl-methyl-amine (60247-14-5)

2,3-Dimethylphenol (526-75-0) + potassium methyl sulfate (562-54-9) → 2,3-dimethylanisole (2944-49-2)

Conditions	Yield
With sodium hydroxide

5-hydroxy-2,3-dihydro-1H-indene (1470-94-6) + potassium methyl sulfate (562-54-9) → 5-methoxyindane (5111-69-3)

Conditions	Yield
With sodium hydroxide; water

4-indanol (1641-41-4) + potassium methyl sulfate (562-54-9) → 4-methoxy-2,3-dihydro-1H-indene (21573-42-2)

Conditions	Yield
With sodium hydroxide

2-mercapto-N-p-tolylacetamide (34282-30-9) + potassium methyl sulfate (562-54-9) → methylsulfanyl-acetic acid p-toluidide (685551-36-4)

Conditions	Yield
With sodium hydroxide

methyl nitrate (598-58-3) + 3-methyluric acid (605-99-2) + potassium methyl sulfate (562-54-9) → 9-methyluric acid (55441-71-9)

Conditions	Yield
at 100℃;

2-mercapto-N-phenylacetamide (4822-44-0) + potassium methyl sulfate (562-54-9) → 2-(methylsulfanyl)-N-phenylacetamide (10156-36-2)

Conditions	Yield
With sodium hydroxide

5-chloro-1H-benzimidazole (4887-82-5) + potassium methyl sulfate (562-54-9) → 1-methyl-5-chlorobenzimidazole (10394-36-2)

Conditions	Yield
With sodium hydroxide

potassium cyanate (590-28-3) + potassium methyl sulfate (562-54-9) → methyl isocyanate (624-83-9)

potassium ethyl xanthogenate (140-89-6) + potassium methyl sulfate (562-54-9) → O-ethyl S-methyl dithiocarbonate (623-54-1)

sodium benzenesulfonate (873-55-2) + potassium methyl sulfate (562-54-9) → Methyl phenyl sulfone (3112-85-4)

Conditions	Yield
With water at 120 - 130℃; im geschlossenen Rohr;

sodium benzylmercaptide (3492-64-6) + potassium methyl sulfate (562-54-9) → [(methylthio)methyl]-benzene (766-92-7)

Conditions	Yield
With water

potassium methyl sulfate (562-54-9) + sodium benzamidate (39536-32-8) → N-methylbenzamide (88070-48-8)

potassium cyanide (151-50-8) + potassium methyl sulfate (562-54-9) → acetonitrile (75-05-8)

Conditions	Yield
bei der Destillation;

potassium cyanide (151-50-8) + potassium methyl sulfate (562-54-9) → methyl isocyanate (593-75-9, 685498-28-6) + acetonitrile (75-05-8)

Conditions	Yield
With water

potassium methyl sulfate (562-54-9) → methylthiol (74-93-1)

Conditions	Yield
With water; potassium hydrosulfide

potassium methyl sulfate (562-54-9) → dimethylsulfide (75-18-3)

Conditions	Yield
With potassium sulphide; water

potassium methyl sulfate (562-54-9) → dimethylselenide (593-79-3)

Conditions	Yield
With sodium selenide

potassium methyl sulfate (562-54-9) → dimethyl diselenide (7101-31-7)

Conditions	Yield
With potassium diselenide

potassium methyl sulfate (562-54-9) → nitromethane (75-52-5) + methyl nitrite (624-91-9)

Conditions	Yield
With alkali nitrite
With alkaline earth nitrite

potassium methyl sulfate (562-54-9) → Methyl fluoride (593-53-3)

Conditions	Yield
With potassium fluoride

potassium methyl sulfate (562-54-9) → Dimethyl ether (115-10-6)

Conditions	Yield
at 220 - 280℃;

potassium methyl sulfate (562-54-9) → methanetrisulfonic acid (54322-33-7)

Conditions	Yield
With sulfuric acid at 100℃;

1,2-dimethoxybenzene (91-16-7) + potassium methyl sulfate (562-54-9) + benzene-1,2-diol (120-80-9) → 2-methoxy-phenol (90-05-1)

Conditions	Yield
With sodium hydrogencarbonate at 170 - 180℃;

Upstream product

• 77-78-1 dimethyl sulfate 
• 93-58-3 benzoic acid methyl ester 
• 7732-18-5 water 
• 2459-25-8 methyl naphthalene-2-carboxylate 
• 2459-24-7 methyl 1-naphthoate 

Downstream Products

• 106-58-1 N,N'-dimethylpiperazine 
• 79-16-3 N-methyl-acetamide 
• 5111-69-3 5-methoxyindane 
• 624-83-9 methyl isocyanate 
• 3112-85-4 methylphenylsulfonate 
• 88070-48-8 N-methylbenzamide 
• 75-05-8 acetonitrile 
• 593-75-9 methyl isocyanate 
• 74-93-1 methylthiol 
• 75-18-3 dimethylsulfide 
• 593-79-3 dimethylselenide 
• 7101-31-7 dimethyl diselenide 
• 75-52-5 nitromethane 
• 624-91-9 methyl nitrite 

Relevant articles and documents

METHOD FOR PRODUCING MONOALKYL SULFATE

PROBLEM TO BE SOLVED: To provide a method for producing high purity monoalkyl sulfate by reacting dialkyl sulfate and alkali metal salt in an organic solvent. SOLUTION: There is provided the method for producing monoalkyl sulfate by reacting dialkyl sulfate represented by the formula (I) and an alkali metal salt represented by the formula (II). (I) (II), where R represents an alkyl group having 1 to 18 carbon atoms or a haloalkyl group having 1 to 18 carbon atoms, M+ represents a lithium ion, a sodium ion or a potassium ion and X- represents an anion species having a primary acid dissociation constant (pKa1) in a water of conjugate acid thereof of 10. COPYRIGHT: (C)2015,JPOandINPIT