6258-35-1

Upstream product

• 5460-32-2 1-iodo-3,4-dimethoxybenzene 
• 107-19-7 propargyl alcohol 
• 62497-24-9 (3,4-dimethoxyphenyl)propynoic acid methyl ester 
• 2859-78-1 4-Bromoveratrole 

Downstream Products

• 3929-47-3 3-(3,4-dimethoxyphenyl)-1-propanol 
• 501098-88-0 3,4-dimethoxyphenylpropynal 
• 1016261-64-5 3-(3,4-dimethoxyphenyl)prop-2-ynyl 3,4,5-trimethoxyphenylcarbamate 
• 1184406-44-7 3,4-dimethoxyphenylpropargyl chloride 
• 1276122-26-9 5-(3,4-dimethoxy-phenyl)-6,8-dihydro-furo[3′,4’:6,7]naphtha[2,3-d][1,3]dioxole 
• 1276122-36-1 4-(3,4-dimethoxyphenyl)-5,6-dimethoxy-1,3-dihydronaphtho[2,3-c]furan 
• 1346682-58-3 1-(3-(3,4-dimethoxyphenyl)prop-2-ynyloxy)-3-(4-methoxyphenyl)propan-2-ol 
• 1346682-60-7 1-(benzo[d][1,3]dioxol-5-yl)-3-(3-(3,4-dimethoxyphenyl)prop-2-ynyloxy)propan-2-ol 
• 1346682-62-9 1-(3,4-dimethoxyphenyl)-3-(3-(3,4-dimethoxyphenyl)prop-2-ynyloxy)propan-2-ol 
• 1346682-44-7 1-(3-(3,4-dimethoxyphenyl)prop-2-ynyloxy)-3-(4-methoxyphenyl)propan-2-one 
• 1346682-46-9 1-(benzo[d][1,3]dioxol-5-yl)-3-(3-(3,4-dimethoxyphenyl)prop-2-ynyloxy)propan-2-one 
• 1346682-48-1 1-(3,4-dimethoxyphenyl)-3-(3-(3,4-dimethoxyphenyl)prop-2-ynyloxy)propan-2-one 
• 6258-38-4 dehydrodimethylconidendrin 
• 1346682-57-2 2-((3-(3,4-dimethoxyphenyl)prop-2-ynyloxy)methyl)oxirane 

Relevant academic research and scientific papers

Cascade reaction including a formal [5?+?2] cycloaddition by use of alkyne-Co2(CO)6 complex

A new cascade reaction including formal [5 + 2] cycloaddition was developed. Treatment of homocinnamyl alcohol and Co2(CO)6-complexed arylpropynal with BF3·OEt2 resulted in the generation of hydrobenzocyclohepta

Cobalt-Catalyzed Asymmetric Hydroboration/Cyclization of 1,6-Enynes with Pinacolborane

We report a cobalt-catalyzed asymmetric hydroboration/cyclization of 1,6-enynes with catalysts generated from Co(acac)2 and chiral bisphosphine ligands and activated in situ by reaction with pinacolborane (HBpin). A variety of oxygen-, nitrogen

Concise synthesis of arylnaphthalene lignans by regioselective intramolecular anionic diels-alder reactions of 1,7-diaryl-1,6-diynes

Total synthesis of phyllamycin A and C, justicidin B, and retrojusticidin B from simple arylalkynyl alcohols and (3,4-methylenedioxyphenyl)propynal was accomplished in 4-5 steps by employing an intramolecular anionic Diels-Alder reaction as the key step.

Synthesis of arylnaphthalene lignan scaffold by gold-catalyzed intramolecular sequential electrophilic addition and benzannulation

An intramolecular approach to generate compounds containing an arylnaphthalene lignan scaffold in high yields is presented. It involves a sequential intramolecular electrophilic attack of carbonyl on arylalkyne followed by benzannulation catalyzed by gold salt. AuCl3 in combination with AgSbF6 works better to effect this transformation. Selected products have been converted into arylnaphthalene lactone natural products such as justicidin E, taiwanin C, and retrojusticidin B (Figure presented).

The Enantiospecific Nicholas Reaction

The enantiospecific Nicholas reaction, i.e. cobalt-promoted Friedel-Crafts reaction leading from chiral reactant to chiral product, was demonstrated for the first time. - Key Words: Nicholas reaction; enantiospecific; cobalt-stabilized carborations; 1-ethynyltetralin