6259-66-1

Usage

Uses

Used in Textile Industry:
2-Naphthol-3,6,8-trisulfonic acid is used as a dyeing and printing agent for its ability to impart color and enhance the appearance of textiles.
Used in Paper Industry:
In the paper industry, 2-Naphthol-3,6,8-trisulfonic acid is utilized as a dyeing and printing agent to improve the color and visual appeal of paper products.
Used in Analytical Chemistry:
2-Naphthol-3,6,8-trisulfonic acid is used as a colorimetric reagent for the detection of metal ions, taking advantage of its complex-forming ability with these ions.
Used as a Fluorescent Probe:
In analytical chemistry, 2-Naphthol-3,6,8-trisulfonic acid also serves as a fluorescent probe for the determination of various substances in solution, leveraging its fluorescent properties for sensitive detection.
Used in Medical Diagnostics:
2-Naphthol-3,6,8-trisulfonic acid has been studied for its potential use in medical diagnostics, where its fluorescent and complex-forming characteristics could contribute to the development of diagnostic tools.
Used in Biological Research as a Tracer:
In biological research, 2-Naphthol-3,6,8-trisulfonic acid is considered for use as a tracer, allowing researchers to track and visualize specific biological processes or substances due to its fluorescent properties.

InChI:InChI=1/C10H8O10S3/c11-8-4-7-5(2-10(8)23(18,19)20)1-6(21(12,13)14)3-9(7)22(15,16)17/h1-4,11H,(H,12,13,14)(H,15,16,17)(H,18,19,20)

Synthetic route

7-ethoxycarbonyloxy-naphthalene-1,3,6-trisulfonic acid ; potassium salt → 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1)

Conditions	Yield
beim Trocknen;

β-naphthol (135-19-3) → 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1)

Conditions	Yield
With sulfuric acid at 70 - 80℃; man gibt noch H2SO4 hinzu und erhitzt laengere Zeit auf 120grad; endlich fuegt man rauchende Schwefelsaeure (mit 40prozent SO3) hinzu und erwaermt laengere Zeit auf 150grad;
With sulfuric acid; sulfur trioxide at 140 - 160℃; das Reaktionsprodukts verarbeitet man dann in der ueblichen Weise auf das Natriumsalz;
With sulfuric acid at 70 - 80℃; man gibt noch H2SO4 hinzu und erhitzt laengere Zeit auf 120grad; endlich fuegt man rauchende Schwefelsaeure (mit 40prozent SO3) hinzu und erwaermt laengere Zeit auf 150grad;
With sulfuric acid; sulfur trioxide at 140 - 160℃; das Reaktionsprodukts verarbeitet man dann in der ueblichen Weise auf das Natriumsalz;

2,2-dioxo-2λ6-naphth[2,3-c][1,2]oxathiete-5,7-disulfonic acid + diluted NaOH-solution → 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1)

sulfuric acid (7664-93-9) + β-naphthol (135-19-3) → 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1)

Conditions	Yield
at 140 - 160℃;
at 140 - 160℃;

3-hydroxy-naphthalene-disulfonic acid-(2.7) → 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1)

Conditions	Yield
With sulfuric acid at 175℃;

7-hydroxy-naphthalene-disulfonic acid-(1.3) → 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1)

Conditions	Yield
With sulfuric acid at 175℃;

water (7732-18-5) + 7-ethoxycarbonyloxy-naphthalene-1,3,6-trisulfonic acid ; potassium salt → 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1)

Conditions	Yield
beim Aufbewahren;

7-ethoxycarbonyloxy-naphthalene-1,3,6-trisulfonyl chloride (856210-17-8) + alcoholic alkaline solution → 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1)

7-ethoxycarbonyloxy-naphthalene-1,3,6-trisulfonyl chloride (856210-17-8) + aqueous alkaline solution → 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1)

chloroform (67-66-3) + 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 8-formyl-7-hydroxy-naphthalene-1,3,6-trisulfonic acid

Conditions	Yield
With sodium hydroxide

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 7-aminonaphthalene-1,3,6-trisulfonic acid (118-03-6)

Conditions	Yield
With ammonia

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 4,6,7-trihydroxy-naphthalene-2-sulfonic acid (6357-98-8)

Conditions	Yield
With alkali durch Verschmelzen;
With alkali durch Verschmelzen;

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 6,7-dihydroxy-naphthalene-1,3-disulfonic acid (149141-96-8) + 3,5-dihydroxynaphthalene 2,7-disulfonic acid (81344-22-1)

Conditions	Yield
durch die Natronschmelze;

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 7-hydroxy-naphthalene-1,3,6-trisulfonyl chloride

Conditions	Yield
With chlorosulfonic acid at 130℃;

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 8-amino-7-hydroxy-naphthalene-1,3,6-trisulfonic acid (88246-96-2)

Conditions	Yield
durch Reduktion von Azoderivaten;

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 2-naphthol-3,6-disulphonic acid (148-75-4)

Conditions	Yield
With sodium amalgam

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) + chloroformic acid ethyl ester (541-41-3) → 7-ethoxycarbonyloxy-naphthalene-1,3,6-trisulfonic acid ; potassium salt

Conditions	Yield
With potassium hydroxide

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 1.6.7-trioxy-naphthalene-sulfonic acid-(3)

Conditions	Yield
setzt man die Natronschmelze laenger fort;

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) + ammonia (7664-41-7) → 7-aminonaphthalene-1,3,6-trisulfonic acid (118-03-6)

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 3,5-dihydroxynaphthalene 2,7-disulfonic acid (81344-22-1) + 2.3-dioxy-naphthalene-disulfonic acid-(5.7)(?)

Conditions	Yield
bei der Natronschmelze;
durch die Natronschmelze;

chlorosulfonic acid (7790-94-5) + 7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 7-hydroxy-naphthalene-1,3,6-trisulfonyl chloride

Conditions	Yield
at 130℃;

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) + sodium amalgam → 2-naphthol-3,6-disulphonic acid (148-75-4)

7-hydroxy-naphthalene-1,3,6-trisulfonic acid (6259-66-1) → 2,3,5-trihydroxynaphthalene (26628-39-7)

Conditions	Yield
Multi-step reaction with 2 steps 1: alkali / durch Verschmelzen View Scheme

Upstream product

• 135-19-3 β-naphthol 
• 7664-93-9 sulfuric acid 
• 856210-17-8 7-ethoxycarbonyloxy-naphthalene-1,3,6-trisulfonyl chloride 
• 7732-18-5 water 

Downstream Products

• 118-03-6 7-aminonaphthalene-1,3,6-trisulfonic acid 
• 148-75-4 2-naphthol-3,6-disulphonic acid 

Relevant academic research and scientific papers

Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member

A reactive dye of the formula STR1 in which: F is a radical selected from the group consisting of metal-free or metal-containing monoazo or disazo dyes containing at least one --SO3 H group, anthraquinone dyes, sulfophthalocyanine dyes, formazan dyes, phenazine dyes, oxazine dyes and nitroaryl dyes, R is hydrogen, C1 -C4 alkyl which is unsubstituted or substituted with --COOH or --SO3 H, cyanoethyl, or hydroxyethyl, X is fluorine, chlorine, bromine, --SO3 H, phenylsulfonyl or C1 -C4 -alkylsulfonyl, p is 1 or 2 and A is a radical of the formula STR2 in which: Y is chlorine, bromine, fluorine, --OH, --OSO3 H, --O-acyl, --CN, --COOH, --COO--C1 -C4 -alkyl, --CONH2 or --SO2 --Z, the group designated "alk" is a straight or branched polymethylene radical having 2 to 6 carbon atoms, V is STR3 hydrogen or C1 -C4 -alkyl which is unsubstituted or substituted by C1 -C2 -alkoxy, carboxyl, sulfo, halogen or hydroxy, Z is β-halogenoethyl, vinyl or β-acetoxyethyl, or A is a radical of the formulae STR4 in all of which R' is C1-6 -alkyl or hydrogen, Z is as defined above, o is 0 to 6, and m is 2 to 6.

Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge

The invention relates to novel useful reactive dyes of the formula I STR1 in which: F is a radical selected from the group consisting of metal-free or metal-containing monoazo or disazo dyes containing at least one --SO3 H group, anthraquinone dyes, sulfophthalocyanine dyes, formazan dyes, phenazine dyes, oxanine dyes and nitroaryl dyes, R is hydrogen, C1 -C4 alkyl which is unsubstituted or substituted with --COOH or --SO3 H, cyanoethyl, or hydroxyethyl, X is fluorine, chlorine, bromine, --SO3 H, phenylsulfonyl or C1 -C4 -alkylsulfonyl, P is 1 or 2 and A is a radical of the formula STR2 in which: the groups designated "alk" are independently of each other straight or branched polymethylene radicals having 2 to 6 carbon atoms, and Z is β-halogenoethyl, vinyl, β-sulfatoethyl, β-thiosulfatoethyl or βacetoxyethyl.