62605-89-4

Upstream product

• 121-91-5 isophthalic acid 
• 79-19-6 thiosemicarbazide 
• 333-20-0 potassium thioacyanate 
• 2760-98-7 isophthalic dihydrazide 

Downstream Products

• 7271-30-9 5,5'-(1,3-phenylene)bis(2,4-dihydro-3H-1,2,4-triazole-3-thione) 
• 160847-61-0 benzene-1,3-dicarboxylic acid bis<2-(4-oxo-2-thiazolidinylidene)hydrazide> 
• 160847-55-2 2,2'-<(1,3-phenylene)bis<5,2-(1H-1,2,4-triazoldiyl)thio>>bisacetic acid 
• 160847-52-9 diethyl 2,2'-<(1,3-phenylene)bis<5,2-(1H-,1,2,4-triazolediyl)thio>>bisacetate 
• 1370035-72-5 C₁₄H₁₀Cl₂N₆O₂S₂ 

Relevant academic research and scientific papers

Bonding Ability of Isopthalic Acid-bis(thiosemicarbozone) to Manganese and Cobalt Metal Ions: Preparation, Spectral Investigation, Computational and in vitro Antipathogenic Screening

Manganese and cobalt complexes have been designed and prepared with a tetradentate ligand i.e. isopthalic acid-bis(thiosemicarbozone) (IPBT), which bind to metal ions via donor atoms present in ligand. Different spectroscopic techniques viz. nuclear magnetic resonance, infrared, mass, electronic spin resonance and analytical studies have been used to determine the chemical composition of synthesized IPBT and its Mn(II) and Co(II) complexes. The spectroscopic data exposed that IPBT behaves in a tetradentate (N2S2) mode by having ability to bind with metal ions through N2S2 atoms. An octahedral structure for manganese and cobalt complexes has been suggested on the basis of spectroscopic as well as analytical studies. The ligand (IPBT) and its metal(II) complexes have been screened to determine their antipathogenic activity against some selective microorganisms S. aureus, P. aeruginosa, E. coli, A. niger, M. phasolina and P. glomerata. In this experimental work, well diffusion and poisoned food techniques have been introduced for screening purpose and as standard drugs neomycin and chlorothalonil have been used. Data for antipathogenic screening exposed that metal complexes exerted higher activity towards all examined microbes (bacteria and fungi) even than ligand.

Synthesis and biological evaluation of new tetra-aza macrocyclic scaffold constrained oxadiazole, thiadiazole and triazole rings

A new series of N,N′-(benzene-1,3-diyldi-1,3,4-oxadiazole-5,2-diyl) bis{2-[(5-benzene-1,3-diyl-1,3,4-oxadiazol-2-yl)amino]acetamide}(macrocycle 1), N,N′-(benzene-1,3-diyldi-1,3,4-thiadiazole-5,2-diyl)bis{2-[(5-benzene-1, 3-diyl-1,3,4-thiadiazol-2-yl)amino