626201-29-4Relevant academic research and scientific papers
The SmI2/TEU--Mediated Cyclization of Unsaturated Halides
McDonald, Chriss E.,Bendorf, Holly D.,Mauck, Joseph R.,McAtee, Christopher C.,Green, Ahren I.,Ciccarelli, David J.,Bendyk, Cassandra A.,Conrad, Brandon J.,Delgado, Angelique T.
, p. 5685 - 5689 (2020)
The combination of SmI2 and the conjugate base of triethylurea (TEU-) has been shown to favor the cyclization of unsaturated halides over direct reduction to a much greater extent than other SmI2-based reductants. Aryl, heteroaryl, and alkyl halides (X =
Bis(2-cycloazylindolyl)titanium Complexes: Synthesis, Characterization, and the Catalytic Behaviors towards Hydroamination and Ring-opening Polymerization of ε-Caprolactone
Zhao, Jing-Jing,Pei, Hao,Chen, Yan-Mei,Lu, Ning,Liu, Jin-Na,Hu, Jin-Fa,Liu, Wei,Li, Wu,Li, Yahong
, p. 1322 - 1328 (2015/06/30)
The ligands 2-pyrazol-1-yl-1H-indole (HL1) and 2-1,2,4-triazol-1-yl-1H-indole (HL2) individually reacted with Ti(NMe2)4 in tetrahydrofuran to form the corresponding complexes Ti(L1)2(NMe2)2 (1) and Ti
Selective N-alkylation of aromatic primary amines catalyzed by bio-catalyst or deep eutectic solvent
Singh, Balvant,Lobo, Hyacintha,Shankarling, Ganapati
experimental part, p. 178 - 182 (2011/10/05)
Biocatalysts or deep eutectic solvents (DES) are effective for selective N-alkylation of various aromatic primary amines. These methods avoided complexity of multiple alkylations giving products in good yields. Both DES and lipase can be recycled and re-used at least five times. In addition, these catalysts are biodegradable, non-toxic and cost-effective.
Palladium-Catalyzed Amination of Aryl Nonaflates
Anderson, Kevin W.,Mendez-Perez, Maria,Priego, Julian,Buchwald, Stephen L.
, p. 9563 - 9573 (2007/10/03)
The first detailed study of the palladium-catalyzed amination of aryl nonaflates is reported. Use of ligands 2-4 and 6 allows for the catalytic amination of electron-rich and -neutral aryl nonaflates with both primary and secondary amines. With use of Xantphos 5, the catalytic amination of a variety of functionalized aryl nonaflates resulted in excellent yields of anilines; even 2-carboxymethyl aryl nonaflate is effectively coupled with a primary alkylamine. Moderate yields were obtained when coupling halo-aryl nonaflates with a variety of amines, where in most cases the aryl nonaflate reacted in preference to the aryl halide. Overall, aryl nonaflates are an effective alternative to triflates in palladium-catalyzed C-N bond-forming processes due to their increased stability under the reaction conditions.
