62633-13-0Relevant articles and documents
Near-infrared fluorophores containing benzo[c]heterocycle subunits
Meek, Scott T.,Nesterov, Evgueni E.,Swager, Timothy M.
supporting information; experimental part, p. 2991 - 2993 (2009/05/07)
(Chemical Equation Presented) The syntheses and spectroscopic properties of eight new push-pull-type near-infrared fluorophores that contain either isobenzofuran or isothianaphthene subunits are presented. The isobenzofuran dyes demonstrate significantly red-shifted absorption compared with their isothianaphthene counterparts, which is attributed to isobenzofuran's more potent pro-quinoidal character.
Isoindolin-1-one derivative and antiarrhythmic agent
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, (2008/06/13)
Isoindolin-1-one compounds represented by the following formula (I); STR1 {wherein n represents an integer of 1 to 6; m represents 0 or 1; R1, R2 and R3 are each independently hydrogen or lower alkyl, and when m is 1, R1 and one of R2 and R3 may form a five-membered or six-membered ring over N atom; X represents hydrogen or hydroxy; Ar represents naphthyl, pyridyl or substituted phenyl represented by the formula (II); Ar and X may form a lactone ring; STR2 [wherein Y represents carboxyl, lower alkoxycarbonyl, carbamoyl, N,N-lower alkyl-substituted carbamoyl or amino represented by the formula (III): STR3 (wherein R6 and R7 are each independently hydrogen, lower alkyl or lower alkanoyl); R4 and R5 are each independently hydrogen, lower alkyl, cyano or halogen]} or a pharmaceutically acceptable acid addition salt or metal salt thereof have an excellent antiarrhythmic activity.
