21528-31-4

Basic information

• Product Name: 2-[4-(dimethylamino)benzoyl]benzoic acid
• Synonyms: 2-[4-(dimethylamino)benzoyl]benzoic acid;Benzoic acid, 2-(4-(dimethylamino)benzoyl)-;Einecs 244-423-0
• CAS NO: 21528-31-4
• Molecular Formula: C₁₆H₁₅NO₃
• Molecular Weight: 269.2952
• EINECS: 244-423-0
• Mol File: 21528-31-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 208-209 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 487.5°Cat760mmHg
• Flash Point: 248.6°C
• Appearance: /
• Density: 1.234g/cm³
• Vapor Pressure: 2.57E-10mmHg at 25°C
• Refractive Index: 1.626
• PKA: 3.40±0.36(Predicted)
• CAS DataBase Reference: 2-[4-(dimethylamino)benzoyl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(dimethylamino)benzoyl]benzoic acid(21528-31-4)
• EPA Substance Registry System: 2-[4-(dimethylamino)benzoyl]benzoic acid(21528-31-4)

Safety Data

• Hazardous Substances Data: 21528-31-4(Hazardous Substances Data)

Usage

Description

2-[4-(dimethylamino)benzoyl]benzoic acid is a chemical compound characterized by the molecular formula C17H17NO3. It is an organic compound that features a benzene ring with two carboxylic acid groups and a dimethylamino group attached to one of the benzene rings. This unique structure endows it with potential applications across various scientific fields, including organic synthesis, pharmaceuticals, and material science.

Uses

Used in Organic Synthesis:
2-[4-(dimethylamino)benzoyl]benzoic acid is utilized as a reagent in organic chemistry reactions, facilitating the synthesis of a wide range of compounds. Its presence in these reactions is crucial for the formation of desired products, making it an indispensable component in the field of organic synthesis.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-[4-(dimethylamino)benzoyl]benzoic acid serves as a building block for the synthesis of various pharmaceutical compounds. Its unique structure and properties contribute to the development of new drugs with potential therapeutic applications.
Used in Material Science:
2-[4-(dimethylamino)benzoyl]benzoic acid is also employed in material science for the development of novel materials with specific properties. Its incorporation into these materials can enhance their performance, making it a valuable component in the advancement of material science.
Overall, the diverse applications of 2-[4-(dimethylamino)benzoyl]benzoic acid highlight its significance in various scientific disciplines, making it a valuable chemical for research and development.

InChI:InChI=1/C16H15NO3/c1-17(2)12-9-7-11(8-10-12)15(18)13-5-3-4-6-14(13)16(19)20/h3-10H,1-2H3,(H,19,20)

Upstream product

• 85-44-9 phthalic anhydride 
• 121-69-7 N,N-dimethyl-aniline 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 861326-54-7 2-[3-(4-dimethylamino-phenyl)-1-oxo-inden-2-yl]-benzaldehyde 
• 7722-84-1 dihydrogen peroxide 
• 7664-93-9 sulfuric acid 
• 7446-70-0 aluminium trichloride 
• 5339-80-0 3,3-bis-p-dimethylaminophenylphthalide  
• 100-05-0 4-nitrobenzenediazonium chloride 

Downstream Products

• 1028367-90-9 C₁₇H₁₇NO₂ 
• 67699-14-3 3-[4-(dimethylamino)phenyl]-3-[N-(4-dimethylaminophenyl)-N-(4-dimethylamino)phenylamino]phthalide 
• 67697-69-2 3-[4-(dimethylamino)-phenyl]-3-(N,N-diphenylamino)phthalide 
• 80508-53-8 1-chloro-4-(p-dimethylaminophenyl)-phthalazine 
• 3159-88-4 3-(4-dimethylamino-3-nitro-phenyl)-3-(4-dimethylamino-phenyl)-phthalide 
• 74453-96-6 methyl o--methyl benzoate 
• 62632-80-8 2-(4,4'-bis-dimethylamino-benzhydryl)-benzoic acid 
• 746608-53-7 2-(4-dimethylamino-3-nitro-benzoyl)-benzoic acid 
• 62633-13-0 3-(4-dimethylaminophenyl)-1,3-dihydro-isobenzofuran-1-one 
• 857005-73-3 2-(4-dimethylamino-benzyl)-benzoic acid 
• 530-44-9 4-(Dimethylamino)benzophenone 
• 3159-92-0 3-(4-dimethylamino-phenyl)-3-(4-hydroxy-phenyl)-phthalide 

Relevant articles and documents

Visible responses under high pressure in crystals: phenolphthalein and its analogues with adjustable ring-opening threshold pressures

The ring-opening reaction of phenolphthalein (PP) crystals under hydrostatic pressure provided by using a diamond anvil cell (DAC) is described in this paper for the first time. The color of the crystals changed into red from colorless visibly. The ring-opening threshold pressures could be adjusted by changing the substituent groups. Mechanochromic responses under hydrostatic pressure could also be achieved in polymer blends, which contributes to their practical applications.

Phthalide compounds, and recording materials using the compounds

The invention relates to a phthalide compound of general formula (I), processes for its production, and recording materials utilizing the compound. (wherein R1 and R3 independently represent an alkyl group, a cycloalkyl group or an aralkyl group; R2 and R4 independently represent methyl or phenyl; R5 and R6 independently represent an alkyl group, a cycloalkyl group, an aralkyl group or an aryl group; R7 represents hydrogen, an alkyl group, an alkoxy group or a cyclo-alkoxy group; R5 and R6 may, taken together with the adjacent nitrogen atom, form a heterocyclic group). Recording materials utilizing the phthalide compound of the invention are suited for reading with any OCR equipped with a light source having an emission wavelength within the range of 570-780 nm.