62635-46-5

Usage

Uses

Used in Pharmaceutical Industry:
N-(2-bromophenyl)ethanethioamide is used as a potential therapeutic agent for various diseases, including thyroid disorders and some types of cancer. Its chemical structure and properties make it a candidate for medicinal chemistry applications.
Used in Chemical Research:
N-(2-bromophenyl)ethanethioamide is used as a research compound in the field of organic chemistry, particularly for studying the synthesis and properties of thioamides and their potential applications in various chemical processes.

InChI:InChI=1/C8H8BrNS/c1-6(11)10-8-5-3-2-4-7(8)9/h2-5H,1H3,(H,10,11)

Upstream product

• 614-76-6 N-acetyl-2-bromoaniline 
• 615-36-1 2-bromoaniline 

Downstream Products

• 444995-70-4 N-(2-bromo-phenyl)-N'-isopropyl-acetamidine 
• 444995-73-7 N-(2-bromo-phenyl)-N'-cyclopentyl-acetamidine 
• 444995-71-5 N-benzyl-N'-(2-bromo-phenyl)-acetamidine 
• 120-75-2 2-Methylbenzothiazole 
• 5805-83-4 1-benzyl-2-methylbenzimidazole 
• 5805-76-5 1-ethyl-2-methyl-1H-benzo[d]imidazole 
• 444995-72-6 N-(2-bromo-phenyl)-N'-(2-methoxy-ethyl)-acetamidine 
• 444995-68-0 N-(2-bromo-phenyl)-N'-methyl-acetamidine 
• 444995-69-1 N'-(2-bromophenyl)-N-ethylethanimidamide 

Relevant academic research and scientific papers

Photocatalyst- And Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp2)-S Formation

A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.

One-pot preparation of 2 (alkly)arylbenzothiazoles from the corresponding o-halobenzanilides

Thionation of o-halobenzanilides was carried out in the presence of Lawesson's reagent. Subsequently, the formed thioamides reacted with cesium carbonate to give the corresponding benzothiazole derivatives in the same pot. Georg Thieme Verlag Stuttgart.

Synthesis of 2-substituted-benzothiazoles by palladium-catalyzed intramolecular cyclization of o-bromophenylthioureas and o-bromophenylthioamides

2-Amino-, and 2-alkyl-benzothiazoles have been efficiently prepared by palladium catalyzed cyclization of o-bromophenylthioureas and o-bromophenylthiamides. Results were best with the Pd2(dba)3/monophosphine catalytic system.

An intramolecular palladium-catalysed aryl amination reaction to produce benzimidazoles

A novel synthesis of benzimidazoles by a palladium-catalysed intramolecular N-arylation reaction from (o-bromophenyl)amidine precursors is described.