6264-66-0

Basic information

• Product Name: 3,4,4'-TRIAMINODIPHENYL ETHER
• Synonyms: 3,4,4’-triaminodiphenyloxide;4-(4-aminophenoxy)-2-benzenediamine;4-(p-aminophenoxy)-o-phenylenediamin;3,4,4'-TRIAMINODIPHENYL ETHER;4-(4-aminophenoxy)-1,2-benzenediamine;4-(4-AMINOPHENOXY)BENZENE-1,2-DIAMINE;3,4,4-TRIAMINODIPHENYL ETHER 98+%;4-Aminophenyl 3,4-diaminophenyl ether
• CAS NO: 6264-66-0
• Molecular Formula: C₁₂H₁₃N₃O
• Molecular Weight: 215.25
• EINECS: 228-425-9
• Mol File: 6264-66-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 150-152 °C
• Boiling Point: 433.9 °C at 760 mmHg
• Flash Point: 246.5 °C
• Appearance: /
• Density: 1.289 g/cm³
• Vapor Pressure: 9.92E-08mmHg at 25°C
• Refractive Index: 1.712
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 5.22±0.10(Predicted)
• CAS DataBase Reference: 3,4,4'-TRIAMINODIPHENYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,4'-TRIAMINODIPHENYL ETHER(6264-66-0)
• EPA Substance Registry System: 3,4,4'-TRIAMINODIPHENYL ETHER(6264-66-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RTECS: SS8080000
• Hazardous Substances Data: 6264-66-0(Hazardous Substances Data)

Usage

General Description

3,4,4'-TRIAMINODIPHENYL ETHER is a chemical compound with the molecular formula C12H13N3O. It is commonly used as a curing agent for epoxy resins in the production of composites, coatings, and adhesives. This chemical is also known for its excellent thermal and chemical resistance, making it ideal for applications in the aerospace, automotive, and electronics industries. Additionally, 3,4,4'-TRIAMINODIPHENYL ETHER is utilized as an intermediate in the synthesis of various dyes and pharmaceuticals. It is a white crystalline solid that is insoluble in water but soluble in organic solvents and has a strong aromatic odor. This chemical is considered to be harmful if swallowed, inhaled, or absorbed through the skin, and should be handled and disposed of with proper safety precautions.

InChI:InChI=1/C12H13N3O/c13-8-1-3-9(4-2-8)16-10-5-6-11(14)12(15)7-10/h1-7H,13-15H2

Upstream product

• 100-00-5 4-chlorobenzonitrile 
• 6149-33-3 4-(4-nitrophenoxy)aniline 
• 103-90-2 4-acetaminophenol 
• 2687-40-3 4-nitrophenyl 4'-acetamidophenyl ether 
• 58688-76-9 4-acetylamino-3,4'-dinitrodiphenyl ether 
• 40257-56-5 4-amino-3,4'-dinitrodiphenyl ether 

Downstream Products

• 86386-79-0 C₄₆H₃₂N₆O₂ 
• 86386-81-4 C₅₂H₃₆N₆O₃ 
• 56073-92-8 methyl (5-(4-aminophenoxy)-1H-benzimidazol-2-yl)carbamate 
• 247939-94-2 bis-{4-[7-(4-amino-phenoxy)-3-phenyl-quinoxalin-2-yl]-phenyl}-methanone 

Relevant articles and documents

Chemical compounds

Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.

Synthesis of methyl 5(6)-(4-aminophenoxy)-and 5(6)-(2-aminophenoxy)-2- benzimidazolyl carbamates and their biological properties

A procedure was developed for preparation of methyl 5(6)-(4-aminophenoxy)- and 5(6)-(2-aminophenoxy)-2-benzimidazolyl carbamates by reaction of 3,4,4′-triaminodiphenyl or 3,4,2′-triaminodiphenyl ethers respectively with methyl cyanocarbamate in water solution in the presence of 7-10 molar excess of acetic acid. The helminthicidal properties, embryotoxicity, and overall toxicity of compounds obtained were estimated.