62677-53-6

Upstream product

• 38274-35-0 1,2,3-triphenylindene 
• 90-99-3 diphenylchloromethane 
• 645-49-8 cis-stilben 
• 60999-93-1 2-benzhydryl-1,3-diphenylpropane-1,3-dione 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 91-01-0 1,1-Diphenylmethanol 
• 5773-56-8 1,2-Diphenylethanol 
• 501-65-5 diphenyl acetylene 

Relevant academic research and scientific papers

Regio- and Stereoselective Synthesis of 1,2,3-Trisubstituted Indanes from Diarylmethanols and Allylamides through Iron(III) Chloride Hexahydrate

An efficient method for the highly regio- and stereoselective synthesis of 1,2,3-trisubstituted indanes from diarylmethanols and allylamides through iron(III) chloride hexahydrate-catalyzed intermolecular [3+2] cycloaddition reaction is reported. A range

Direct Synthesis of Indanes via Iron-Catalyzed Dehydrative Coupling/Friedel–Crafts Cyclization of Two Different Alcohols

We report herein a novel iron-catalyzed cascade dehydrative coupling/Friedel–Crafts cyclization of two different alcohols, providing a variety of indanes, which are ubiquitous substructures found in natural products, pharmaceuticals, and functional materi

An efficient and general iron-catalyzed C-C bond activation with 1,3-dicarbonyl units as a leaving groups

(Chemical Equation Presented) With our compliments: The 1,3-dicarbonyl unit has been shown to be a new and useful leaving group for iron-catalyzed bond cleavage (see scheme). This new strategy can complement the traditional Friedel-Crafts reaction and was applied in the synthesis of indene derivatives.

Synthesis of diastereoisomeric 1,2,3-triphenylindans

The stereoisomers of 1,2,3-triphenylindans were synthesized via 1,2,3-triphenylindan-1-ols. The configurational assignments of all the compounds were made by chemical and spectroscopic methods. An unexpected compound was isolated as a by-product of the Gr

Reactivity of Unsaturated Substrates under Reductive Electron Transfer Conditions. Part 1. Reduction of 1,2,3-Triphenyl-1H-indene with Sodium Metal in Various Solvents

The reduction of 1,2,3-triphenyl-1H-indene 1 with sodium metal in various solvents was carried out in order to compare the results with those previously obtained in the electrochemical reduction of 1 (Hg cathode, dimethylformamide, Bu4N+ClO4- as supporting electrolyte).The most general reaction observed was reduction of the double bond of the pentatomic cycle to afford the corresponding indanes of different configurations.In two cases (1,2-dimethoxyethane, dioxane) this reaction was accompanied by reduction of the C(1)-H bond of 1 with formation of the corresponding anion and hydrogen.No rearrangement or cleavage of groups was observed.In a protic solvent (pentan-1-ol) the results are consistent with a reduction process occurring via protonation of the radical anion of 1, affording quantitatively the isomeric indanes with a slight preference for those of cis-configuration around the C(2)-C(3) bond.In liquid ammonia, in contrast, the results are indicative of a reduction process occurring via protonation of dianionic species, leading to the almost exclusive formation of indanes of trans-configuration around the C(2)-C(3) bond.The self-protonation reaction, which is the characteristic process of reduction of 1 under electrochemical conditions in the absence of specific proton donors, was found to be followed only in the case of tetrahydrofuran, where a pseudo-unimolecular decay of a paramagnetic species, likely the radical anion of 1, could be followed in an EPR cavity.

Electrochemical Reduction of Activated Carbon-Carbon Double Bonds. Part 2. Mechanism and Stereochemistry of the Reduction of Self-protonating Indenes

The reduction at a mercury electrode in dimethylformamide of five variously substituted indenes bearing at least one (acidic) hydrogen at C(1) was carried out, under self-protonation conditions and in the presence of phenol as a proton donor.Reduction occ