38274-35-0Relevant academic research and scientific papers
Synthesis of substituted indene derivatives via silver-catalyzed annulative 1:1 coupling of secondary benzyl alcohols with alkynes
Morisaka, Hideaki,Hirosawa, Keishi,Inai, Yasuhito,Usuki, Yoshinosuke,Satoh, Tetsuya
supporting information, p. 456 - 458 (2021/03/16)
The annulative coupling of secondary benzyl alcohols with internal alkynes efficiently proceeds in the presence of a silver catalyst. The reaction gives 1,2,3-substituted indene derivatives selectively as 1:1 coupling products. The procedure provides a straightforward synthetic route to indenes from readily available starting materials upon treatment with a simple reaction system under mild conditions.
KHMDS mediated synthesis of 9-arylfluorenes from dibenzothiophene dioxides and arylacetonitriles by tandem SNAr-decyanation-based arylation
Mylavarapu, Saketh,Yadav, Mamta,Bhanuchandra
supporting information, p. 7815 - 7819 (2018/11/21)
A straightforward KHMDS mediated synthetic route to 9-arylfluorenes from readily available starting materials has been developed. This reaction involves SNAr reactions of dioxide with arylacetonitriles, followed by decyanation reaction. The pro
Synthesis of multisubstituted indenes via iron-catalyzed domino reaction of benzylic compounds and alkynes
Chen, Yongxin,Li, Kangning,Liu, Xiang,Zhu, Jiaoyan,Chen, Baohua
supporting information, p. 130 - 134 (2013/02/25)
A novel approach to synthesizing multisubstituted indenes by iron-catalyzed domino reaction of benzylic compounds and alkynes under mild conditions was developed. This system could be applied to various available substrates in a one-step synthetic procedure in moderate to good yields. Georg Thieme Verlag Stuttgart · New York.
Synthesis of substituted indenes through iron-catalyzed annulation of benzylic alcohols with alkynes
Bu, Xiuli,Hong, Jianquan,Zhou, Xigeng
supporting information; scheme or table, p. 2111 - 2118 (2011/10/09)
A convenient and efficient method for the synthesis of polysubstituted indenes has been developed by the iron(III) trichloride-catalyzed tandem mono- and dibenzylation/cyclization reactions of benzylic alcohols with alkynes. This method is featured with the easily available starting materials, cheap catalyst, simple manipulation and mild conditions. Copyright
An efficient and general iron-catalyzed C-C bond activation with 1,3-dicarbonyl units as a leaving groups
Li, Huanrong,Li, Wenjuan,Liu, Weiping,He, Zhiheng,Li, Zhiping
supporting information; experimental part, p. 2975 - 2978 (2011/05/05)
(Chemical Equation Presented) With our compliments: The 1,3-dicarbonyl unit has been shown to be a new and useful leaving group for iron-catalyzed bond cleavage (see scheme). This new strategy can complement the traditional Friedel-Crafts reaction and was applied in the synthesis of indene derivatives.
Catalytic regioselective synthesis of structurally diverse indene derivatives from N-benzylic sulfonamides and disubstituted alkynes
Liu, Cong-Rong,Yang, Fu-Lai,Jin, Yi-Zhou,Ma, Xian-Tao,Cheng, Dao-Juan,Li, Nan,Tian, Shi-Kai
supporting information; experimental part, p. 3832 - 3835 (2010/11/17)
An unprecedented protocol has been developed for the regioselective synthesis of structurally diverse indene derivatives from readily accessible N-benzylic sulfonamides and disubstituted alkynes through FeCl 3-catalyzed cleavage of sp3 carbon-nitrogen bonds to generate benzyl cation intermediates. In the presence of 10 mol % of FeCl 3, a broad range of N-benzylic sulfonamides smoothly react with internal alkynes, alkynylcarbonyl compounds, alkynyl chalcogenides, or alkynyl halides to afford various functionalized indene derivatives with extremely high regioselectivity.
Au-catalyzed isomerization of cyclopropenes: a novel approach to indene derivatives
Li, Changkun,Zeng, Yi,Wang, Jianbo
supporting information; experimental part, p. 2956 - 2959 (2009/08/09)
AuPPh3Cl/AgOTf-catalyzed reaction of cyclopropenes is found to be highly efficient, giving indene derivatives in high yields. The reaction is suggested to proceed through gold vinyl carbenoid intermediate.
(η5-triphenylindenyl)Ru(CO)2Cl: A new ruthenium catalyst for the highly efficient racemization of chiral 1-phenylethanol at room temperature
Xi, Qiang,Zhang, Weicheng,Zhang, Xumu
, p. 945 - 947 (2007/10/03)
A new ruthenium complex, (η5-triphenylindenyl)Ru(CO) 2Cl, was synthesized and successfully applied in the racemization of (S)-1-phenylethanol at room temperature. Instead of potassium tert-butoxide, stronger bases such as sodium hydr
Synthesis of diastereoisomeric 1,2,3-triphenylindans
Alesso, Elba N.,Finkielsztein, Liliana M.,Lantano, Beatriz,Bianchi, Daniel E.,Moltrasio Iglesias, Graciela Y.,Aguirre, Jose M.
, p. 149 - 152 (2007/10/03)
The stereoisomers of 1,2,3-triphenylindans were synthesized via 1,2,3-triphenylindan-1-ols. The configurational assignments of all the compounds were made by chemical and spectroscopic methods. An unexpected compound was isolated as a by-product of the Gr
Metal-catalyzed cyclopropene rearrangements for benzannulation: Evaluation of an anthraquinone synthesis pathway and reevaluation of the parallel approach via carbene-chromium complexes
Semmelhack,Ho, Suzzy,Cohen,Steigerwald,Lee,Lee,Gilbert, Adam M.,Wutff, William D.,Ball, Richard G.
, p. 7108 - 7122 (2007/10/02)
The reaction of 3-arylcyclopropenes with Cr(CO)6 and Mo(CO)6 produces naphthols, in an example of metal-promoted benzannulation. Substituents at C- 3 (in addition to aryl) have a strong effect on the success of the process: 3-H deriv
