62682-01-3

Usage

Uses

Used in Pharmaceutical Industry:
2-(2,4-Dichlorophenyl)-5-phenyl-1,3,4-oxadiazole serves as an essential building block for the development of various pharmaceuticals due to its potential anticancer, antifungal, and antimicrobial properties. Its incorporation into drug molecules can enhance their therapeutic effects and target a wide range of diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(2,4-Dichlorophenyl)-5-phenyl-1,3,4-oxadiazole is utilized as a key component in the synthesis of compounds with pesticidal properties, contributing to the development of effective solutions for crop protection and management.
Used in Analytical Chemistry:
2-(2,4-Dichlorophenyl)-5-phenyl-1,3,4-oxadiazole has been investigated for its potential as a fluorescent probe for detecting metal ions. This application allows for the sensitive and selective detection of various metal ions, which is crucial in environmental monitoring and other analytical processes.
Overall, 2-(2,4-Dichlorophenyl)-5-phenyl-1,3,4-oxadiazole is a versatile chemical with a range of potential applications across different industries, highlighting its importance in modern scientific research and development.

InChI:InChI=1/C14H8Cl2N2O/c15-10-6-7-11(12(16)8-10)14-18-17-13(19-14)9-4-2-1-3-5-9/h1-8H

Upstream product

• 5814-06-2 2,4-dichlorobenzohydrazide 
• 65-85-0 benzoic acid 
• 39575-07-0 2,4-Dichlorbenzaldehydbenzoylhydrazon 
• 56882-52-1 ethyl 2,4-dichlorobenzoate 
• 155164-66-2 2-benzoyl-4,5-dichloropyridazin-3(2H)-one 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 613-94-5 benzoic acid hydrazide 
• 39575-21-8 Benzaldehyd-(2,4-dichlorbenzoyl)hydrazon 

Relevant academic research and scientific papers

Microwave-assisted one-step synthesis of 2,5-disubstituted-1,3,4- oxadiazoles using 1,4- bis(triphenylphosphonium)-2-butene peroxodisulfate

A series of 1,3,4-oxadiazoles were efficiently synthesized from the cyclization-oxidation reaction of acyl hydrazones by using 1,4- bis(triphenylphosphonium)-2-butene peroxodisulfate as an oxidant in solvent-free medium under microwave irradiation.

I2-mediated oxidative C-O bond formation for the synthesis of 1,3,4-oxadiazoles from aldehydes and hydrazides

A practical and transition-metal-free oxidative cyclization of acylhydrazones into 1,3,4-oxadiazoles has been developed by employing stoichiometric molecular iodine in the presence of potassium carbonate. The conditions of this cyclization reaction also work well with crude acylhydrazone substrates obtained from the condensation of aldehydes and hydrazides. A series of symmetrical and asymmetrical 2,5-disubstituted (aryl, alkyl, and/or vinyl) 1,3,4-oxadiazoles can be conveniently generated in an efficient and scalable fashion.

A novel, one-pot synthesis of 2,5-disubstituted-1,3,4-oxadiazoles using 1,4-bis(Triphenylphosphonium)-2-butene peroxodisulfate

An efficient and convenient synthesis of 1,3,4-oxadiazoles from aromatic aldehydes, acyl hydrazide, and 1,4- bis(triphenylphosphonium)-2-butene peroxodisulfate is reported. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

A facile procedure for the one-pot synthesis of unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles

Unsymmetrically 2,5-disubstituted 1,3,4-oxadiazoles were efficiently synthesized from the cyclization-oxidation reaction of acyl hydrazones. Also, the synthesis of the title compounds was achieved by the condensation of acyl hydrazides and aromatic aldehydes in the presence of ceric ammonium nitrate in dichloromethane.

Facile synthesis of symmetric and unsymmetric 1,3,4-oxadiazoles using 2-acyl(or aroyl)pyridazin-3-ones

Symmetric and unsymmetric 1,3,4-oxadiazoles were synthesized in situ from hydrazine hydrate and the corresponding 2-acyl-4,5-dichloropyridazin-3-ones as acylating agents in polyphosphoric acid or BF3·OEt2 in excellent yields.