62696-41-7

Upstream product

• 129388-29-0 (R)-2-Hydroxy-2-phenyl-pent-4-enoic acid ethyl ester 
• 172089-40-6 (3R,10aS)-3-Allyl-3-phenyl-10,10a-dihydro-[1,4]oxazino[4,3-a]indole-1,4-dione 
• 20978-66-9 ethyl 2-hydroxy-2-phenyl-4-pentanoate 
• 129286-24-4 5-allyl-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-one 
• 611-71-2 MANDELIC ACID 
• 6337-34-4 2,2-dimethyl-5-phenyl-1,3-dioxolan-4-one 

Downstream Products

• 103383-73-9 (3R,8aS)-3-phenyl-3-(2-propenyl)-1,4-dioxo-3,4,6,7,8,8a-hexahydro-1H-pyrrolo<2,1-c><1,4>oxazine 
• 94726-51-9 methyl (2S,1'S)-N-<(1-hydroxy-1-phenyl-3-butenyl)-formyl>prolinate 

Relevant academic research and scientific papers

Isomannide and isosorbide as new chiral auxiliaries for the stereoselective synthesis of tertiary α-hydroxy acids

Isomannide and isosorbide are selectively protected to provide new chiral auxiliaries suitable for the preparation of enantiopure tertiary α-hydroxy acids. Diastereoselective additions of organozinc reagents on the derived phenylglyoxylates afford the desired α-hydroxy acids with 60-99% ee after saponification. Both absolute configurations of the α-hydroxy acids can be accessed, by adapted choice of either the starting diol or the protecting group.

Highly Stereoselective Allylation to Chiral α-Keto Amides Derived from (S)-Indoline-2-carboxylic Acid. Astmmetric Synthesis of Functionalized Tertiary Homoallyl Alcohols.

The diastereoselective addition of allylsilane and - stannane in the presence of Lewis acids to new chiral α-keto amides derived from (S)-indoline-2-carboxylic acid resulted in optically active tertiary homoallyl alcohols with extremely high diastereosele

Pig Liver Esterase Catalyzed Hydrolyses of Racemic α-Substituted α-Hydroxy Esters

Pig liver esterase catalyzed hydrolyses of some α-substituted α-hydroxy esters give product acids and recovered esters in 9-94percent enantiomeric excess.The observed enantiomeric selectivity could be rationalized using a recently proposed active site mod