627086-06-0Relevant articles and documents
Efficient route to the pineal hormone melatonin by radical-based indole synthesis
Thomson, Douglas W.,Commeureuc, Aurelien G. J.,Berlin, Stefan,Murphy, John A.
, p. 3631 - 3641 (2003)
The hormone melatonin, which is known to have a range of important biological effects, has been prepared in a high-yielding route that features formation of the indole nucleus by radical cyclization. Mediation of the radical cyclization by tristrimethylsilylsilane (TTMSS) is more efficient than by N-ethylpiperidine hypophosphite.
