
Synthetic Communications p. 3631 - 3641 (2003)
Update date:2022-08-04
Topics:
Thomson, Douglas W.
Commeureuc, Aurelien G. J.
Berlin, Stefan
Murphy, John A.
The hormone melatonin, which is known to have a range of important biological effects, has been prepared in a high-yielding route that features formation of the indole nucleus by radical cyclization. Mediation of the radical cyclization by tristrimethylsilylsilane (TTMSS) is more efficient than by N-ethylpiperidine hypophosphite.
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