6271-30-3

Usage

Uses

Used in Pharmaceutical Industry:
Hydrazinecarboxylic acid, 1-methylethyl ester is used as an intermediate in the synthesis of various pharmaceutical compounds. It plays a crucial role in the production of drugs that treat a wide range of medical conditions.
Used in Agricultural Industry:
Hydrazinecarboxylic acid, 1-methylethyl ester is also used as an intermediate in the manufacturing of agricultural products. It contributes to the development of pesticides and other agrochemicals that help protect crops and enhance agricultural productivity.
It is important to handle and store hydrazinecarboxylic acid, 1-methylethyl ester with caution, and to use appropriate protective equipment when working with this substance. Additionally, proper disposal methods should be followed to avoid environmental contamination.

InChI:InChI=1/C4H10N2O2/c1-3(2)8-4(7)6-5/h3H,5H2,1-2H3,(H,6,7)

Upstream product

• 82998-18-3 isopropyl 1H-imidazole-1-carboxylate 
• 108-23-6 isopropyl chloroformate 

Downstream Products

• 1101187-28-3 isopropyl 2-(pyridin-2-yl)benzoate 
• 41096-33-7 isopropyl 3-hydroxy-3-phenylbutyrate 

Relevant academic research and scientific papers

Palladium-Catalyzed Oxidative C–H Alkoxycarbonylation of Arenes with Alkylcarbazates Directed by N-Heterocyclic Substituents

With alkyl carbazates as the green ester source, a novel palladium-catalyzed oxidative free radical carbonylative transformation of the C–H bond on aromatic rings to produce esters has been developed. Good yields of the corresponding products have been obtained with wide functional group tolerance and excellent regioselectivity. A variety of alkyl carbazates are found to be suitable reactants for the ortho-alkoxycarbonylation on the aromatic ring.

Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?

Starting from potent aldehyde inhibitors with poor drug properties, derivatization to semicarbazones led to the identification of a series of semicarbazone-based cathepsin K inhibitors with greater solubility and better pharmacokinetic profiles than their parent aldehydes. Furthermore, a representative semicarbazone inhibitor attenuated bone resorption in an ex vivo rat calvarial bone resorption model. However, based on enzyme inhibition comparisons at neutral pH, semicarbazone hydrolysis rates, and 13C NMR experiments, these semicarbazones probably function as prodrugs of aldehydes.