34101-22-9

Basic information

• Product Name: (E)-2-(4-chlorophenyl)ethenyl phenyl sulfone
• CAS NO: 34101-22-9
• Molecular Formula: C₁₄H₁₁ClO₂S
• Molecular Weight: 278.7539
• Mol File: 34101-22-9.mol
• Article Data: 54

Chemical Properties

• Boiling Point: 471.4°C at 760 mmHg
• Flash Point: 238.9°C
• Density: 1.314g/cm³
• Vapor Pressure: 1.32E-08mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: (E)-2-(4-chlorophenyl)ethenyl phenyl sulfone(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-chlorophenyl)ethenyl phenyl sulfone(34101-22-9)
• EPA Substance Registry System: (E)-2-(4-chlorophenyl)ethenyl phenyl sulfone(34101-22-9)

Safety Data

• Hazardous Substances Data: 34101-22-9(Hazardous Substances Data)

Usage

General Description

(E)-2-(4-chlorophenyl)ethenyl phenyl sulfone, also known as E-4-CPVEPS, is a chemical compound with the molecular formula C14H9ClO2S. It is a yellow crystalline solid that is commonly used in synthetic organic chemistry as a building block for the preparation of a variety of pharmaceuticals and agrochemicals. (E)-2-(4-chlorophenyl)ethenyl phenyl sulfone has a wide range of potential applications, including as a cross-linking agent in polymerization reactions, as a fluorescent imaging agent in biological studies, and as a starting material for the synthesis of new materials with specialized properties. It is important to handle and use this chemical with care, as it may be harmful if ingested or inhaled, and can cause irritation to the skin and eyes.

Upstream product

• 2788-86-5 4-Chlorostyrene oxide 
• 873-55-2 sodium benzenesulfonate 
• 1073-67-2 4-vinylbenzyl chloride 
• 98-09-9 benzenesulfonyl chloride 
• 5535-48-8 PVS 
• 673-41-6 p-chlorobenzenediazonium tetrafluoroborate 
• 1679-18-1 4-Chlorophenylboronic acid 
• 637-87-6 1-Chloro-4-iodobenzene 
• 873-73-4 4-n-chlorophenylacetylene 
• 98-11-3 benzenesulfonic acid 
• 6272-36-2 1,2-bis(benzenesulfonyl)hydrazine 
• 32291-83-1 1-(4'-chlorophenyl)-2-(phenylsulfanyl)ethene 
• 3112-85-4 methylphenylsulfonate 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 911832-91-2 methyl 4-phenylsulfonyl-3-(4-chlorophenyl)butyrate 
• 1245924-50-8 (2-[(2R,3S)-3-(4-chlorophenyl)-4-(phenylsulfonyl)butan-2-yl]phenyl)(p-tolyl)-(S)-sulfoxide 
• 1245924-63-3 [(2S,3R)-3-(2-((S)-p-tolylsulfinyl)phenyl)-4-phenyl-1-(phenylsulfonyl)butan-2-yl]-4-chlorobenzene 
• 89130-31-4 (Z)-1-chloro-4-(3-methylbut-1-en-1-yl)benzene 
• 1363721-85-0 C₂₈H₂₄ClFO₃S₂ 

Relevant articles and documents

Controlled Synthesis of β-Keto Sulfones and Vinyl Sulfones under Electrochemical Oxidation

Selective sulfonylation and oxosulfonylation of alkenes with sulfinates have been developed via anodic oxidation in an undivided cell. The novel electrosynthetic method provided β-keto sulfones and vinyl sulfones with good to excellent yields in the absence of any transition metal catalyst and oxidants. Mechanism studies show that two different pathways involved in these two transformations.

PhB(OH)2-Promoted Electrochemical Sulfuration-Formyloxylation of Styrenes and Selectfluor-Mediated Oxidation-Olefination

We report a PhB(OH)2-promoted electrochemical sulfuration-formyloxylation reaction of styrenes employing commercially available thiophenols/thiols as thiolating agents. Specifically, metal catalysts and external chemical oxidants are not needed in the reaction for the formation of β-formyloxy sulfides, and these sulfides can be further converted to (E)-vinyl sulfones via the Selectfluor-mediated oxidation-olefination. Notably, on the basis of this electrochemical oxidation strategy, β-hydroxy sulfide, β-formyloxy sulfoxide, β-formyloxy sulfone, and (E)-vinyl sulfoxide can also be easily prepared.

Intermolecular [2 + 2] Photocycloaddition of α,β-Unsaturated Sulfones: Catalyst-Free Reaction and Catalytic Variants

2-Aryl-1-sulfonyl-substituted cyclobutanes were prepared in an intermolecular [2 + 2] photocycloaddition from various α,β-unsaturated sulfones and olefins upon irradiation at λ = 300 nm (26 examples, 60-99% yield). Lewis acids catalyzed the [2 + 2] photocycloaddition of 2-benzimidazolyl styryl sulfones. At short wavelengths, the latter substrates underwent C-S bond cleavage but AlBr3 (5 mol %) allowed for an intermolecular reaction with 2,3-dimethyl-2-butene at longer wavelengths. A chiral-at-metal Lewis acid (2 mol %) facilitated an enantioselective reaction (up to 77% ee).