62740-57-2Relevant academic research and scientific papers
Thiophilic Allylation of Dithioesters and Trithiocarbonates
Capperucci, Antonella,Degl'Innocenti, Alessandro,Ferrara, M. Cristiana,Bonini, Bianca F.,Mazzanti, Germana,et al.
, p. 161 - 164 (1994)
Reaction of dithioesters and trithiocarbonates with silylated nucleophiles under fluoride ion conditions affords a novel example of silyl mediated regiochemical control in the thiophilic functionalization.
Direct Synthesis of Unsymmetrical Dithioacetals
Bognar, Sabine,van Gemmeren, Manuel
supporting information, p. 4859 - 4863 (2021/02/03)
Dithioacetals are a frequently used motif in synthetic organic chemistry and have recently seen increasing attention as structural motif in promising antiviral agents against plant pathogens. Most existing reports, however, only discuss symmetrical dithioacetals. Examples of mixed dithioacetals are scarce and no general method for the selective synthesis of these compounds exists. Herein, a synthetically simple general one-step protocol was developed for the synthesis of a broad range of unsymmetrical dithioacetals consisting of one aromatic and one aliphatic thiol moiety from the corresponding aldehyde/thiol mixture. The mixed S,S-acetals were obtained in high yields, and a great variety of functional groups was tolerated. Kinetic control enabled an excellent selectivity in regard to the unsymmetrical dithioacetal.
An efficient synthesis of unsymmetrical dithioacetals from sulfoxides and thiols by the magnesium amide-induced pummerer-type reaction
Kobayashi, Kazuhiro,Kawakita, Masataka,Akamatsu, Hideki,Morikawa, Osamu,Konishi, Hisatoshi
, p. 2645 - 2647 (2007/10/03)
It has been found that the reactions of sulfoxides bearing hydrogen(s) at the α-position (R 1 SOCHR 2R 3: R 1 = alkyl or Ph; R 2 = H, alkyl, or Ph; R 3 = H or Me) with thiols (R 4SH: R 4 = alkyl or aryl) in the presence of the (diisopropylamino)magnesium
