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2,4-DIOXO-1-PHENYL-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBONITRILE, commonly known as furosemide, is a potent diuretic medication used to treat various conditions such as congestive heart failure, liver disease, and kidney disorders. It functions by inhibiting the reabsorption of sodium and chloride in the kidneys, resulting in increased urine production and reduced fluid retention in the body. As a loop diuretic, furosemide is available in both oral and intravenous forms and is considered safe and effective when used under the guidance of a healthcare professional. However, it may cause side effects like dehydration, electrolyte imbalances, and low blood pressure if not properly monitored.

6275-84-9

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6275-84-9 Usage

Uses

Used in Medical Applications:
2,4-DIOXO-1-PHENYL-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBONITRILE is used as a diuretic for the treatment of conditions such as congestive heart failure, liver disease, and kidney disorders. It helps in reducing fluid retention in the body by increasing urine production, thereby alleviating symptoms associated with these conditions.
Used in Congestive Heart Failure Treatment:
In the medical industry, 2,4-DIOXO-1-PHENYL-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBONITRILE is used as a diuretic to manage congestive heart failure. It helps in reducing the workload on the heart by decreasing fluid buildup and improving the pumping efficiency of the heart.
Used in Liver Disease Management:
2,4-DIOXO-1-PHENYL-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBONITRILE is used as a diuretic in the treatment of liver disease to help manage fluid retention and reduce the strain on the liver.
Used in Kidney Disorder Treatment:
In the medical industry, 2,4-DIOXO-1-PHENYL-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBONITRILE is used as a diuretic for the management of kidney disorders. It aids in enhancing urine production, which helps in the removal of excess fluid and waste products from the body, thus supporting kidney function.
Used in Oral and Intravenous Administration:
2,4-DIOXO-1-PHENYL-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBONITRILE is used in both oral and intravenous forms for medical use, allowing for flexible administration options based on the patient's condition and healthcare professional's recommendations.

Check Digit Verification of cas no

The CAS Registry Mumber 6275-84-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,7 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6275-84:
(6*6)+(5*2)+(4*7)+(3*5)+(2*8)+(1*4)=109
109 % 10 = 9
So 6275-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H7N3O2/c12-6-8-7-14(11(16)13-10(8)15)9-4-2-1-3-5-9/h1-5,7H,(H,13,15,16)

6275-84-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,4-dioxo-1-phenylpyrimidine-5-carbonitrile

1.2 Other means of identification

Product number -
Other names 5-cyano-1-phenyluracil

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6275-84-9 SDS

6275-84-9Relevant academic research and scientific papers

A multi-component reaction to 5-cyanouracils: Synthesis and mechanistic study

Zhuang, Bo-Ren,Hsu, Gien-Jow,Sung, Kuangsen

, p. 3399 - 3404 (2007/10/03)

Acetonitrile as a solvent, excess of primary amines as general bases, and a reflux condition make the multi-component reactions of (2-cyanoacetyl) carbamate 1, ethyl orthoformate, and primary amines form 5-cyanouracils 4a-c feasibly. Mechanistic studies o

Synthesis of 1-Substituted 5-Cyanouracils

Wolfbeis, Otto S.

, p. 182 - 185 (2007/10/02)

Condensation of (cyanoacetyl)urea (1) with aniline and trimethoxymethane affords (3-anilino-2-cyanoacryloyl)urea (2a), which thermally cyclizes to form strongly fluorescent 5-cyano-1-phenyluracil (3a).By using 2-aminopyridine or trimethoxymethane, other u

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