6279-84-1

Basic information

• Product Name: 3-(3-methoxyphenoxy)propanenitrile
• Synonyms: 3-(3-methoxyphenoxy)propanenitrile
• CAS NO: 6279-84-1
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.2
• Mol File: 6279-84-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 29.5-30.5 °C
• Boiling Point: 333.2°C at 760 mmHg
• Flash Point: 135.7°C
• Appearance: /
• Density: 1.081g/cm³
• Vapor Pressure: 0.000139mmHg at 25°C
• Refractive Index: 1.507
• CAS DataBase Reference: 3-(3-methoxyphenoxy)propanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-methoxyphenoxy)propanenitrile(6279-84-1)
• EPA Substance Registry System: 3-(3-methoxyphenoxy)propanenitrile(6279-84-1)

Safety Data

• Hazardous Substances Data: 6279-84-1(Hazardous Substances Data)

Usage

General Description

3-(3-methoxyphenoxy)propanenitrile is a chemical compound with the molecular formula C10H11NO2. It is a nitrile compound that consists of a propanenitrile group attached to a 3-methoxyphenoxy group. This chemical has potential applications in the field of organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is also used as an intermediate in the production of various types of compounds. The presence of the nitrile functional group makes it a versatile building block for the synthesis of a wide range of organic molecules. Additionally, the 3-methoxyphenoxy group can contribute to the compound's biological activity and can be utilized for the design of biologically active compounds.

InChI:InChI=1/C10H11NO2/c1-12-9-4-2-5-10(8-9)13-7-3-6-11/h2,4-5,8H,3,7H2,1H3

Upstream product

• 150-19-6 O-methylresorcine 
• 3245-45-2 1-(2-bromoethoxy)-3-methoxybenzene 
• 151-50-8 potassium cyanide 
• 107-13-1 acrylonitrile 

Downstream Products

• 10493-09-1 7,3',4'-trimethoxyflavanone 
• 25826-69-1 4',7-dimethoxyflavanone 
• 21785-09-1 7-methoxyflavanone 
• 55947-36-9 5-methoxyflavanone 
• 1181403-94-0 C₁₀H₁₁ClO₃ 
• 5802-17-5 6-methoxychroman-4-one 
• 21112-64-1 (2-hydroxy-4-methoxyphenyl)(phenyl)methanone 
• 6965-78-2 2-benzyl-5-methoxyphenol 
• 131-57-7 Benzophenone-3 
• 30779-91-0 (3E)-2,3-dihydro-7-methoxy-3-(phenylmethylene)-4H-1-benzopyran-4-one 
• 76285-73-9 3-benzyl-7-methoxy-4-chromanone 
• 76285-80-8 4--3-benzyl-7-methoxychroman 
• 76285-82-0 4--3-benzyl-7-methoxychroman 
• 76285-79-5 4-(p-acetoxyphenyl)-3-benzyl-7-methoxychroman 

Relevant articles and documents

Facile access to chiral 4-substituted chromanes through Rh-catalyzed asymmetric hydrogenation

Rh/ZhaoPhos-catalyzed asymmetric hydrogenation of a series of (E)-2-(chroman-4-ylidene)acetates was successfully developed to prepare various chiral 4-substituted chromanes with high yields and excellent enantioselectivities (up to 99percent yield, 98percent ee). Moreover, the gram-scale hydrogenation could be performed well in the presence of 0.02 molpercent catalyst loading (TON = 5000), the hydrogenation product was easily converted to access other important compounds, which demonstrated the synthetic utility of this asymmetric catalytic methodology.

Studies towards the stereoselective α-hydroxylation of flavanones. Biosynthetic significance

The enolates of various propiophenones, chromanones, and also analogues of naturally occurring flavanones were stereoselectively hydroxylated at the ?-position, by employing commercially available enantiopure oxaziridines, to afford the desired ?-hydroxylated target molecules in good to exceptional stereoselectivities and in moderate to good chemical yields. A mechanistic rationale is presented to account for the stereoselectivities achieved. These in vitro results were tentatively related to the stereoselective biosynthesis of enantio-enriched dihydroflavonols while questions were raised about the authenticity of certain natural compounds. CSIRO 2008.

Synthesis and Nematicidal Activity of Phenoxypropionic Acid Derivatives

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