6280-30-4Relevant academic research and scientific papers
Fimctlonalized tetrazoles from cyanogen azide with secondary amines
Joo, Young-Hyuk,Shreeve, Jean'ne M.
experimental part, p. 3573 - 3578 (2009/10/26)
Secondary amines react with cyanogen azide at ambient temperature in water/acetonitrile to provide tetrazole derivatives directly. The scope and limitations with regard to steric hindrance of the amine are discussed. Although reaction yields are moderate, 29-81%, the cyanogen azide reactions provide a direct and versatile route to functionalized tetrazoles that: may be especially useful considering the diversity of amines suitable for this transformation.
A general route to 5-aminotetrazoles
Katritzky, Alan R.,Rogovoy, Boris V.,Kovalenko, Katherine V.
, p. 4941 - 4943 (2007/10/03)
Various di- and trisubstituted (benzotriazolyl)- carboximidamides were used for the preparation of N,N-di-and 1,N,N-trisubstituted 5-aminotetrazoles 3a-e and 6a-d under mild conditions in good to excellent yields.
