62807-94-7 Usage
Classification
Organic compound, Triazene
Function
Potent and selective inhibitor of mutant BRAFV600E, a common oncogenic driver in human cancer cells
Potential use
Cancer therapy, particularly for melanoma and other solid tumors
Status
Has shown promising results in preclinical studies as a targeted therapy for cancer, but requires further research and clinical trials to fully understand its safety and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 62807-94-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,8,0 and 7 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 62807-94:
(7*6)+(6*2)+(5*8)+(4*0)+(3*7)+(2*9)+(1*4)=137
137 % 10 = 7
So 62807-94-7 is a valid CAS Registry Number.
62807-94-7Relevant academic research and scientific papers
Nitrosation with Sodium Hexanitrocobaltate(III)
Stefane, Bogdan,Kocevar, Marijan,Polanc, Slovenko
, p. 7165 - 7169 (2007/10/03)
Na3Co(NO2)6 has been investigated as a new reagent for the nitrosation of various substrates containing an amino functionality. Reactions took place in an aqueous solution of the reagent. The pH of the reaction mixture remained in the range 4.3-5. Thus, hydrazides were transformed to the corresponding acyl azides, and the reactions with arenesulfonyl hydrazines afforded arenesulfonyl azides. Treatment of aromatic amines with Na3Co(NO2)6 gave 1,3-diaryltriazenes in excellent yields; coupling of the initially formed diazo compound to the electron rich aromatic ring was also observed. Nitrosation of aliphatic amines was not possible due to complex formation with the reagent.
