6282-52-6Relevant academic research and scientific papers
One-pot synthesis of ω-bromoesters from aromatic aldehydes and diols using pyridinium hydrobromide perbromide
Aoyama, Tadashi,Takido, Toshio,Kodomari, Mitsuo
, p. 1989 - 1992 (2007/10/03)
A simple and efficient one-pot procedure has been developed for the synthesis of ω-bromoesters from aromatic aldehydes and diols in the presence of pyridinium hydrobromide perbromide (PHPB) and triethoxymethane in which aldehyde reacts first with diol and the product, cyclic acetal, reacts with PHPB to give the final product, ω-bromoesters.
BROMINATION OF DIMETHYLACETALS WITH Br2-CHLOROTRIMETHYLSILANE-NaBr
Bellesia, Franco,Boni, Monica,Ghelfi, Franco,Pagnoni, Ugo Maria
, p. 629 - 632 (2007/10/02)
α-Bromodimethylacetals are obtained in excellent yields by treating dimethylacetals with Br2-NaBr-chlorotrimethylsilane in CH3OH/CH3CN (2:1). The method is suitable for large scale preparation.
