6283-41-6

Basic information

• Product Name: 1,3,4-trimethylpyridinium
• CAS NO: 6283-41-6
• Molecular Formula: C₈H₁₂N*I
• Molecular Weight: 122.187
• Mol File: 6283-41-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,3,4-trimethylpyridinium(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-trimethylpyridinium(6283-41-6)
• EPA Substance Registry System: 1,3,4-trimethylpyridinium(6283-41-6)

Safety Data

• Hazardous Substances Data: 6283-41-6(Hazardous Substances Data)

Usage

General Description

1,3,4-trimethylpyridinium is a quaternary ammonium compound with the chemical formula C8H12N. It is a salt formed by the reaction of three methyl groups with the pyridine molecule, resulting in a positively charged nitrogen atom. 1,3,4-trimethylpyridinium is used in various applications such as in the synthesis of pharmaceuticals, as a corrosion inhibitor in metal treatment, and as a component in surfactants and detergents. It also has antimicrobial properties and is used as an active ingredient in certain disinfectants and antiseptic solutions. Additionally, 1,3,4-trimethylpyridinium has potential applications in the field of organic chemistry and materials science, making it a versatile and important chemical compound.

Upstream product

• 583-58-4 3,4-Lutidin 
• 74-88-4 methyl iodide 

Downstream Products

• 102472-70-8 2-(4-methoxy-benzyl)-1,3,4-trimethyl-piperidine 
• 54395-67-4 2-(p-methoxybenzyl)-1,4,5-trimethyl-2,3,3,6-tetrahydropyridine 
• 54395-66-3 2-(p-methoxybenzyl)-1,3,4-trimethyl-2,3,3,6-tetrahydropyridine 
• 75963-54-1 dimethyl-<(2Z)-2,3-dimethylpenta-2,4-dienyl>(3-phenylprop-2-ynyl)ammonium bromide 
• 50876-61-4 cinnamyldimethyl-<(2Z)-2,3-dimethylpenta-2,4-dienyl>ammonium bromide 
• 75954-83-5 (5Z)-3-dimethylamino-5,6-dimethyl-1-phenylocta-5,7-dien-1-yne 
• 75954-81-3 3-dimethylamino-4,5-dimethyl-1-phenyl-4-vinyl-5-en-1-yne 
• 10556-12-4 5,6-Dimethylazulen 
• 97889-73-1 1,4,5-Trimethyl-6-(4-methylsulfanyl-benzyl)-1,2,3,6-tetrahydro-pyridine 
• 42529-29-3 (+/-)-3,6,11syn-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benz[d]azocine 
• 132674-91-0 4-(1,3,4-Trimethyl-[2]piperidylmethyl)-phenol 
• 87626-30-0 rel-(2R,6S,11S)-6,11-dimethyl-3-(3,4,5-trimethoxyphenethyl)-1,2,3,6-tetrahydro-2,6-methano-3-benzazocine 
• 87680-51-1 rel-(2R,6R,11S)-6,11-dimethyl-3-(3,4,5-trimethoxyphenethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine 
• 42529-29-3 (6R,11R)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine 

Relevant articles and documents

A Short synthesis of benzomorphane analgesics (±)-Metazocine and (±)-Phenazocine

A three step synthesis of (±)-metazocine and (±)-phenazocine starting with 3,4-lutidine is described. The key step involves Lewis acid promoted lithiation/electrophilic substitution reaction of N-alkyl-3,4-dimethyl- 1,2,5,6- tetrahydropyridine. Copyright

Benzomorphans useful as NMDA receptor antagonists

Compounds of the formula I STR1 are disclosed. In this formula, R is a member selected from the group consisting of --CR 1 R 2 R 3, hydroxy, an alkoxy group having 1 to 4 carbon atoms and --NR 4 R 5, in which at most one of R 1, R 2 and R 3 is hydrogen and the remainder are each independently selected from the group consisting of an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 2 to 4 carbon atoms, an alkynyl group having 2 to 4 carbon atoms, a cycloalkyl group having 3 to 7 carbon atoms, a cycloalkylalkyl having 4 to 9 carbon atoms and a 3 to 6 membered cyclic ether; R 4 and R 5 are each independently hydrogen or an alkyl group having 1 to 4 carbon atoms; R 6 and R 7 are each independently hydrogen or an alkyl group having 1 to 4 carbon atoms; and R 8 is hydrogen, an alkyl group having 1 to 4 carbon atoms, hydroxy, an alkoxy group having 1 to 4 carbon atoms or halogen. Salts of these compounds are also disclosed. Also disclosed are pharmaceutical compositions of these compounds with a pharmaceutically acceptable carrier, the use of these materials as N-methyl-D-aspartate receptor antagonists, processes for preparing these compounds and salts, and methods to treat cerebral diseases by administering an effective amount of these compounds, salts or compositions.

Base Catalysed Rearrangements involving Ylide Intermediates. Part 7. The Rearrangements of Allyl(pentadienyl)- and Propionyl(pentadienyl)-ammonium Cations. The Sigmatropic Rearrangement.

The base catalysed rearrangements of the cations (7), (17), (22), and (27) gave the enamines (9), (18), (23), and (28), which on hydrolysis yielded the aldehyde (10), (19), (24), and (29) respectively.The reactions are shown to be concerted sigmatropic rearrangements proceeding via a nine-membered transition state involving 10? electrons.The base catalysed rearrangements of the 3-phenylprop-2-ynyl (pentadienyl) ammonium cations (51), (52), (60), and (61), however yield only the products of , , and sigmatropic rearrangements.