6283-71-2

Basic information

• Product Name: 2-Cyanobutanedioicacid,dimethylester
• Synonyms: Dimethyl Cyanosuccinate;2-Cyanosuccinic acid dimethyl ester;DiMethyl 2-Cyanosuccinate
• CAS NO: 6283-71-2
• Molecular Formula: C₇H₉NO₄
• Molecular Weight: 171.15
• Mol File: 6283-71-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 287.9 °C at 760 mmHg
• Flash Point: 124.1 °C
• Appearance: /
• Density: 1.181g/cm³
• Vapor Pressure: 0.00241mmHg at 25°C
• Refractive Index: 1.436
• CAS DataBase Reference: 2-Cyanobutanedioicacid,dimethylester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyanobutanedioicacid,dimethylester(6283-71-2)
• EPA Substance Registry System: 2-Cyanobutanedioicacid,dimethylester(6283-71-2)

Safety Data

• Hazardous Substances Data: 6283-71-2(Hazardous Substances Data)

Usage

General Description

2-Cyanobutanedioic acid, dimethyl ester is a compound with the chemical formula C6H7NO4. It is a colorless liquid with a slightly fruity odor, and it is commonly used as a chemical intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a solvent and a reagent in organic synthesis. 2-Cyanobutanedioicacid,dimethylester is considered to be a hazardous substance and must be handled with caution. It is important to follow proper safety procedures and use protective equipment when working with 2-Cyanobutanedioic acid, dimethyl ester to avoid potential health risks.

InChI:InChI=1/C7H9NO4/c1-11-6(9)3-5(4-8)7(10)12-2/h5H,3H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 105-39-5 chloroacetic acid ethyl ester 
• 105-56-6 ethyl 2-cyanoacetate 
• 96-34-4 methyl chloroacetate 
• 105-34-0 methyl 2-cyanoacetate 

Downstream Products

• 865834-15-7 1-[2,6-dichloro-4-pentafluorosulfanyl-phenyl]-5-hydroxy-1H-pyrazole-3-carbonitrile 
• 1086395-66-5 2-methyl-2,7-diazaspiro[4.5]decane 
• 1086395-12-1 7-methyl-2,7-diazaspiro[4.5]decane 
• 84454-41-1 2-Cyano-2-(1-phenyl-ethyl)-succinic acid dimethyl ester 
• 84763-53-1 Dimethyl-1-cyan-1-(3-oxocyclohexyl)-1,2-ethandicarboxylat 

Relevant articles and documents

Synthesis and differential functionalisation of pyrrolidine and piperidine based spirodiamine scaffolds

The synthesis and differential substitution/protection of a series of spirodiamine scaffolds are described. Methods for selective access to the two mono-N-methyl isomers based on 2,7-diazaspiro[4.5]decane are also described. Key precursors associated with this chemistry are prone to rearrangement and methods for circumventing this issue are reported. While direct mono-carbamoylation (Boc) was not efficient, selective deprotection of doubly Boc-protected derivatives derived from symmetrical diamines provided mono-Boc variants. N-Arylation, exemplified by a series of monosubstituted spirodiamines incorporating the 2-chloro-5-pyridyl moiety, which is a privileged nicotinic agonist substructure, has also been carried out to provide monoarylated secondary and tertiary spirodiamines variants.

SUBSTITUTED ARYLPYRAZOLES

This invention relates to a range of C4 substituted aryl pyrazoles of Formula (I) including those 1-arylpyrazoles in which the 4-position is substituted with an acyclic substituent, a cycloalkyl ring structure or heterocyclic ring structure and which comp