6283-71-2

Usage

Uses

Used in Pharmaceutical Industry:
2-Cyanobutanedioic acid, dimethyl ester is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Cyanobutanedioic acid, dimethyl ester is utilized as a chemical intermediate in the production of pesticides and other agricultural chemicals. Its properties contribute to the effectiveness and performance of these products.
Used as a Solvent:
2-Cyanobutanedioic acid, dimethyl ester is employed as a solvent in various chemical processes. Its ability to dissolve a wide range of substances makes it a valuable asset in the field of organic synthesis.
Used as a Reagent in Organic Synthesis:
As a reagent, 2-Cyanobutanedioic acid, dimethyl ester is involved in numerous organic synthesis reactions. Its versatility and reactivity enable it to participate in the formation of a variety of organic compounds.
Safety Precautions:
Given its classification as a hazardous substance, it is imperative to handle 2-Cyanobutanedioic acid, dimethyl ester with care. Adhering to proper safety procedures and using appropriate protective equipment is essential to minimize potential health risks associated with its use.

InChI:InChI=1/C7H9NO4/c1-11-6(9)3-5(4-8)7(10)12-2/h5H,3H2,1-2H3

Upstream product

• 96-34-4 methyl chloroacetate 
• 105-34-0 methyl 2-cyanoacetate 
• 105-39-5 chloroacetic acid ethyl ester 
• 67-56-1 methanol 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 84763-53-1 Dimethyl-1-cyan-1-(3-oxocyclohexyl)-1,2-ethandicarboxylat 
• 84454-41-1 2-Cyano-2-(1-phenyl-ethyl)-succinic acid dimethyl ester 
• 865834-15-7 1-[2,6-dichloro-4-pentafluorosulfanyl-phenyl]-5-hydroxy-1H-pyrazole-3-carbonitrile 
• 1086395-66-5 2-methyl-2,7-diazaspiro[4.5]decane 
• 1086395-12-1 7-methyl-2,7-diazaspiro[4.5]decane 

Relevant academic research and scientific papers

Synthesis and differential functionalisation of pyrrolidine and piperidine based spirodiamine scaffolds

The synthesis and differential substitution/protection of a series of spirodiamine scaffolds are described. Methods for selective access to the two mono-N-methyl isomers based on 2,7-diazaspiro[4.5]decane are also described. Key precursors associated with this chemistry are prone to rearrangement and methods for circumventing this issue are reported. While direct mono-carbamoylation (Boc) was not efficient, selective deprotection of doubly Boc-protected derivatives derived from symmetrical diamines provided mono-Boc variants. N-Arylation, exemplified by a series of monosubstituted spirodiamines incorporating the 2-chloro-5-pyridyl moiety, which is a privileged nicotinic agonist substructure, has also been carried out to provide monoarylated secondary and tertiary spirodiamines variants.

Substituted arylpyrazoles

This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.

SUBSTITUTED ARYLPYRAZOLES

This invention relates to a range of C4 substituted aryl pyrazoles of Formula (I) including those 1-arylpyrazoles in which the 4-position is substituted with an acyclic substituent, a cycloalkyl ring structure or heterocyclic ring structure and which comp

One-Pot Synthesis of cis Fixed β-Diketones of Bicycloalkanes, 2

Starting from 2-cycloalken-1-ones 1 the substituted cis fixed β-diketones of bicycloalkanes 4 have been obtained by a combined Michael addition of α,α,ω-alkanetricarboxylates (and related species) 2 and Dieckmann cyclization of the intermediates 3.Reactions of the β-diketone system as well as modifications of the disubstituted malonate system of 4 are reported.