628331-20-4

Basic information

• Product Name: 1H-Pyrazole-3-carboxylic acid, 5-(phenylmethoxy)-, methyl ester
• CAS NO: 628331-20-4
• Molecular Formula: C12H12N2O3
• Molecular Weight: 232.239
• Mol File: 628331-20-4.mol

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-3-carboxylic acid, 5-(phenylmethoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-3-carboxylic acid, 5-(phenylmethoxy)-, methyl ester(628331-20-4)
• EPA Substance Registry System: 1H-Pyrazole-3-carboxylic acid, 5-(phenylmethoxy)-, methyl ester(628331-20-4)

Safety Data

• Hazardous Substances Data: 628331-20-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 40711-33-9 5-hydroxy-2H-pyrazole-3-carboxylic acid ethyl ester 

Downstream Products

• 888741-05-7 methyl 3-(benzyloxy)-1-isobutyl-1H-pyrazole-5-carboxylate 
• 628331-21-5 3-benzyloxy-1-isopropyl-1H-pyrazole-5-carboxylic acid methyl ester 

Relevant articles and documents

ARYLALKANOIC ACID DERIVATIVE

A compound represented by the general formula (I): [wherein Ar represents an optionally substituted aromatic ring; Xa, Xc, Ya, Yc, Z1, and Z2 each represents a bond, O, S, -CO-, -CS-, -CR3(OR4)-, -NR5-, -SO-, -SO2-, -CONR6-, or -NR6CO- (R3, R4, R5, and R6 are as defined in the description); Xb and Yb each represents a bond or a C1-20 divalent hydrocarbon group; R1 represents an optionally substituted hydrocarbon group; ring A represents an aromatic ring (other than benzimidazole) which may be further substituted; n is an integer of 1-8; ring B represents an aromatic ring (other than oxazole) which may be further substituted; W represents a C1-20 divalent saturated hydrocarbon group; and R2 represents -OR8 or -NR9R10 (R8, R9, and R10 are as defined in the description)] or a salt of the compound. It is useful as a preventive/therapeutic agent for diabetes, etc.

1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY

A compound represented by the formula (1) wherein ring A is a ring optionally having 1 to 3 substituents; ring B is a 1,2-azole ring which may further have 1 to 3 substituents; Xa, Xb and Xc are the same or different and each is a bond, - O -, - S - and the like; Ya is a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; Yb and Yc are the same or different and each is a bond or a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; ring C is a monocyclic aromatic ring which may further have 1 to 3 substituents; and R represents -OR4 (R4 is hydrogen atom or optionally substituted hydrocarbon group) and the like, or a salt thereof or a prodrug thereof is useful as an agent for the prophylaxis or treatment of diabetes and the like.