628331-76-0

Upstream product

• 41873-65-8 ethyl 2-(2-hydroxyphenyl)acetate 
• 415949-73-4 methyl (2-benzyloxy-3-bromophenyl)acetate 
• 22446-37-3 methyl (2-hydroxyphenyl)acetate 
• 553-86-6 benzofuran-2(3H)-one 
• 628331-75-9 methyl (2-benzyloxy-3-cyanophenyl)acetate 
• 628331-74-8 methyl 2-(3-bromo-2-hydroxyphenyl)acetate 

Relevant academic research and scientific papers

ORAL COMPLEMENT FACTOR D INHIBITORS

Disclosed are compounds of formula (I), and pharmaceutically acceptable salts thereof, which are inhibitors of the complement system. Also provided are pharmaceutical compositions comprising such a compound, and methods of using the compounds and compositions in the treatment or prevention of a disease or condition characterized by aberrant complement system activity.

1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY

A compound represented by the formula (1) wherein ring A is a ring optionally having 1 to 3 substituents; ring B is a 1,2-azole ring which may further have 1 to 3 substituents; Xa, Xb and Xc are the same or different and each is a bond, - O -, - S - and the like; Ya is a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; Yb and Yc are the same or different and each is a bond or a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; ring C is a monocyclic aromatic ring which may further have 1 to 3 substituents; and R represents -OR4 (R4 is hydrogen atom or optionally substituted hydrocarbon group) and the like, or a salt thereof or a prodrug thereof is useful as an agent for the prophylaxis or treatment of diabetes and the like.