628333-86-8 Usage
Uses
Used in Pharmaceutical Industry:
1-[2-[BIS(TERT-BUTYL)PHOSPHINO]PHENYL]-3,5-DIPHENYL-1H-PYRAZOLE is used as a catalyst for the palladium-catalyzed cross-coupling of alkynes and cyclization of diketones. Its application in this industry is due to its ability to facilitate the formation of new carbon-carbon bonds, which are essential in the synthesis of various pharmaceutical compounds.
Used in Chemical Synthesis:
In the field of chemical synthesis, 1-[2-[BIS(TERT-BUTYL)PHOSPHINO]PHENYL]-3,5-DIPHENYL-1H-PYRAZOLE is used as a catalyst for heterocyclization reactions. Its application in this area is attributed to its ability to promote the formation of heterocyclic compounds, which are important building blocks in the synthesis of various organic molecules, including pharmaceuticals, agrochemicals, and materials.
Used in Material Science:
1-[2-[BIS(TERT-BUTYL)PHOSPHINO]PHENYL]-3,5-DIPHENYL-1H-PYRAZOLE is also used in material science as a catalyst for the synthesis of novel materials with specific properties. Its application in this field is due to its potential to facilitate the formation of complex molecular structures that can be used in the development of advanced materials with unique properties, such as improved conductivity, strength, or stability.
Check Digit Verification of cas no
The CAS Registry Mumber 628333-86-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,8,3,3 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 628333-86:
(8*6)+(7*2)+(6*8)+(5*3)+(4*3)+(3*3)+(2*8)+(1*6)=168
168 % 10 = 8
So 628333-86-8 is a valid CAS Registry Number.
InChI:InChI=1/C29H33N2P/c1-28(2,3)32(29(4,5)6)27-20-14-13-19-25(27)31-26(23-17-11-8-12-18-23)21-24(30-31)22-15-9-7-10-16-22/h7-21H,1-6H3
628333-86-8Relevant academic research and scientific papers
Alternative biarylphosphines for use in the palladium-catalyzed amination of aryl halides
Singer, Robert A.,Caron, Stephane,McDermott, Ruth E.,Arpin, Patrice,Do, Nga M.
, p. 1727 - 1731 (2007/10/03)
Two families of biarylphosphine ligands were prepared for use in the Pd-catalyzed amination reaction. The first series investigated was derived from N-phenylpyrroles, and the second, was derived from N-phenylpyrazoles. While the pyrrole ligands were not as general in substrate scope, one of the readily prepared pyrazole ligands (R = t-Bu) was found to have a fairly broad substrate scope.
