62867-79-2Relevant academic research and scientific papers
Synthesis of Globotriaosylceramide (Gb3) and Isoglobotriaosylceramide (isoGb3)
Qiu, Dongxu,Schmidt, Richard R.
, p. 217 - 224 (2007/10/02)
The synthesis of globotriaosylceramide (1) was based on O-galactosyl trichloroacetimidate 5α as donor and 4b-O-unprotected lactose 7 as acceptor; 7 was readily accessible from lactose.Glycosylation by an "inverted procedure" afforded preferentially the α-
Glycosyl Imidates, 42.- Selectively Protected Lactose and 2-Azido Lactose, Building Blocks for Glycolipid Synthesis
Jung, Karl-Heinz,Hoch, Monika,Schmidt, Richard R.
, p. 1099 - 1106 (2007/10/02)
Performing regioselective alkylation at 3'-OH of benzyl β-lactoside 1 by the stannylation method we prepared the 3'-OH- and 4'-OH-unprotected lactose derivatives 5 and 10 and the 4'-OH-unprotected lactose derivative 9 containing a different protecting gro
Total synthesis of globotriaosyl-E and Z-ceramides and isoglobotriaosyl-E-ceramide.
Koike,Sugimoto,Sato,Ito,Nakahara,Ogawa
, p. 189 - 208 (2007/10/02)
Stereoselective, total synthesis of O-alpha-D-galactopyranosyl-(1----4) -O-beta-D-galactopyranosyl-(1----4)-O-beta-D-glucopyranosyl-(1----1)-N -tetracosanoyl-[2S,3R,4E (and 4Z)]-sphingenine and O-alpha-D -galactopyranosyl-(1----3)-O-beta-D-galactopyranosyl-(1----4)-O-beta-D -glucopyranosyl-(1----1)-N-tetracosanoyl-(2S,3R,4E)-sphin gen ine was achieved by using O-(2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosyl) -(1----4)-O-(2,3,6-tri-O-acetyl-beta-D-galactopyranosyl)-(1----4)-2,3,6- tri-O-acetyl-alpha-D-glucopyranosyl trichloroacetimidate, O-(2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosyl) -(1----4)-O-(2,3,6-tri-O-acetyl-beta-D-galactopyranosyl)-(1----4)-2,3,6- tri-O-acetyl-alpha (and beta)-D-glucopyranosyl fluoride, and O-(2,3,4,6-tetra-O-acetyl-alpha-D -galactopyranosyl)-(1----3)-O-(2,3,6-tri-O-acetyl-beta-D-galactopyran osyl)-(1----4)-2,3,6-tri-O-acetyl-alpha-D-glucopyranosyl trichloroacetimidate.
Building Units of Oligosaccharides, XXXVI. - Investigation of Reactivity in Tri-and Pentasaccharide Syntheses. Improved Synthesis of the Pentasaccharide Chain of the Forssman Antigen
Paulsen, Hans,Buensch, Almuth
, p. 2204 - 2215 (2007/10/02)
The dependence of selectivity and yield upon the initial saccharide's reactivity is shown for the syntheses of the trisaccharides 7, 8, 9, and 12.From 8 comes the trisaccharide halide 15 which, together with 22 in a block synthesis, yields the pentasaccha
