62869-57-2

Basic information

• Product Name: Furo[3,4-f]-1,3-benzodioxol-5(7H)-one, 7-hydroxy-
• Synonyms: 7-hydroxy-7H-furo[3',4':4,5]benzo[1,2-d][1,3]dioxol-5-one;Furo[3,4-f]-1,3-benzodioxol-5(7H)-one,7-hydroxy;7-hydroxyfuro[3,4-f][1,3]benzodioxol-5(7H)-one;5,6-(methylenedioxy)phthalaldehydic acid;3-Hydroxy-5,6-dioxymethylenphthalid
• CAS NO: 62869-57-2
• Molecular Formula: C9H6O5
• Molecular Weight: 194.14100
• Mol File: 62869-57-2.mol

Chemical Properties

• Melting Point: 165-167 °C
• Boiling Point: 461.8±45.0 °C(Predicted)
• Density: 1.699±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Furo[3,4-f]-1,3-benzodioxol-5(7H)-one, 7-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Furo[3,4-f]-1,3-benzodioxol-5(7H)-one, 7-hydroxy-(62869-57-2)
• EPA Substance Registry System: Furo[3,4-f]-1,3-benzodioxol-5(7H)-one, 7-hydroxy-(62869-57-2)

Safety Data

• Hazardous Substances Data: 62869-57-2(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 

Downstream Products

• 51877-66-8 4,5-methylendioxyphtalaldehydic acid 

Relevant articles and documents

General Method for the Synthesis of Phthalaldehydic Acids and Phthalides from o-Bromobenzaldehydes via Ortho-Lithiated Aminoalkoxides

A general method for the synthesis of phthalaldehydic acids and phthalides, many of which are key intermediates in natural product synthesis, has been developed. o-Bromobenzaldehydes 1a-f were first protected in situ as α-morpholinoalkoxides by reaction with lithium morpholide.Treatment of the α-morpholinoalkoxides 3a-f with n-butyllithium (to exchange bromine with lithium) followed by sequential treatment with solid CO2 and dilute acid afforded the phthalaldehydic acids 6a-f, respectively.Reduction of 6a-f with NaBH4 in EtOH furnished the phthalides 7a-f, respectively, in nearly quantitative yields.Efficient methods for the synthesis of the o-bromobenzaldehydes 1a-d, which were not readily available, are also described.