62882-03-5Relevant academic research and scientific papers
Warming Up to Oxazole: Noncryogenic Oxazole Metalation and Negishi Coupling Development
Calimsiz, Selcuk,Geier, Michael J.,Humphreys, Luke D.,Scott, Mark E.,Wang, Xiaotian
, p. 1776 - 1781 (2019)
This report details the development of several suitable noncryogenic metalation conditions for the synthesis of oxazole zincate. Subsequent rounds of high-throughput catalyst screening ultimately led to the identification of several suitable Pd sources th
Highly regioselective palladium-catalyzed direct arylation of oxazole at C-2 or C-5 with aryl bromides, chlorides, and triflates
Strotman, Neil A.,Chobanian, Harry R.,Guo, Yan,He, Jiafang,Wilson, Jonathan E.
supporting information; experimental part, p. 3578 - 3581 (2010/11/04)
Complementary palladium-catalyzed methods for direct arylation of oxazole with high regioselectivity (>100:1) at both C-5 and C-2 have been developed for a wide range of aryl and heteroaryl bromides, chlorides, iodides, and triflates. C-5 arylation is pre
Preparation of 2-substituted oxazoles
Pandit, Chennagiri R.,Polniaszek, Richard P.,Thottathil, John K.
, p. 2427 - 2432 (2007/10/03)
A simple and economical method for 2-substituted oxazole synthesis and its scope are described.
