Welcome to LookChem.com Sign In|Join Free
  • or
6-chloro-N-(4-chlorobenzyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a complex organic compound with the molecular formula C14H11Cl2N5. It is a derivative of pyrazolo[3,4-d]pyrimidin-4-amine, featuring a 6-chloro substituent, a 4-chlorobenzyl group attached to the nitrogen atom, and a methyl group at the 1-position. 6-chloro-N-(4-chlorobenzyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine is characterized by its unique chemical structure, which contributes to its potential applications in various fields, such as pharmaceuticals or chemical research. Due to its specific functional groups and molecular arrangement, it may exhibit distinct chemical properties and reactivity compared to other pyrazolo[3,4-d]pyrimidin-4-amine derivatives.

6289-06-1

Post Buying Request

6289-06-1 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

6289-06-1 Usage

Molecular structure

Contains a pyrazolo[3,4-d]pyrimidin-4-amine core with a 6-chloro group and a 4-chlorobenzyl substituent. Also contains a methyl and an amino group.

Class

Pyrazolopyrimidines

Biological activities

Potential anti-cancer, anti-inflammatory, and anti-viral properties

Potential applications

Pharmaceutical research

Further research

Needed to fully understand potential uses and effects

Check Digit Verification of cas no

The CAS Registry Mumber 6289-06-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,8 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6289-06:
(6*6)+(5*2)+(4*8)+(3*9)+(2*0)+(1*6)=111
111 % 10 = 1
So 6289-06-1 is a valid CAS Registry Number.

6289-06-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-chloro-benzyl)-(6-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine

1.2 Other means of identification

Product number -
Other names (4-Chlor-benzyl)-(4-nitro-phenyl)-sulfid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6289-06-1 SDS

6289-06-1Downstream Products

6289-06-1Relevant academic research and scientific papers

The identification of a novel lead class for phosphodiesterase 2 inhibition by fragment-based drug design

Forster, Ashley B.,Abeywickrema, Pravien,Bunda, Jaime,Cox, Christopher D.,Cabalu, Tamara D.,Egbertson, Melissa,Fay, John,Getty, Krista,Hall, Dawn,Kornienko, Maria,Lu, Jun,Parthasarathy, Gopal,Reid, John,Sharma, Sujata,Shipe, William D.,Smith, Sean M.,Soisson, Stephen,Stachel, Shawn J.,Su, Hua-Poo,Wang, Deping,Berger, Richard

, p. 5167 - 5171 (2017/11/10)

We have identified a novel PDE2 inhibitor series using fragment-based screening. Pyrazolopyrimidine fragment 1, while possessing weak potency (Ki = 22.4 μM), exhibited good binding efficiencies (LBE = 0.49, LLE = 4.48) to serve as a start for structure-based drug design. With the assistance of molecular modeling and X-ray crystallography, this fragment was developed into a series of potent PDE2 inhibitors with good physicochemical properties. Compound 16, a PDE2 selective inhibitor, was identified that exhibited favorable rat pharmacokinetic properties.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 6289-06-1