62903-23-5

Basic information

• Product Name: 4-(5-Chloro-2-hydroxyphenyl)-4-oxobutanoic Acid
• Synonyms: 4-(5-Chloro-2-hydroxyphenyl)-4-oxobutanoic Acid
• CAS NO: 62903-23-5
• Molecular Weight: 228.632
• Mol File: 62903-23-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-(5-Chloro-2-hydroxyphenyl)-4-oxobutanoic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-Chloro-2-hydroxyphenyl)-4-oxobutanoic Acid(62903-23-5)
• EPA Substance Registry System: 4-(5-Chloro-2-hydroxyphenyl)-4-oxobutanoic Acid(62903-23-5)

Safety Data

• Hazardous Substances Data: 62903-23-5(Hazardous Substances Data)

Upstream product

• 108-30-5 succinic acid anhydride 
• 106-48-9 4-chloro-phenol 
• 623-12-1 4-chloromethoxybenzene 
• 15571-99-0 4-Chlorophenyl Hydrogen Succinate 
• 63213-94-5 5-chloro-2-methoxy-γ-oxobenzenebutanoic acid 
• 99854-21-4 Methyl 4-(5-Chloro-2-hydroxyphenyl)-4-oxobutanoate 

Downstream Products

• 107774-17-4 4-(5-chloro-2-methoxy-phenyl)-4-oxo-butyric acid ethyl ester 
• 103857-54-1 5-(5-chloro-2-methoxy-phenyl)-dihydro-furan-2-one 
• 100119-68-4 4-(5-chloro-2-hydroxy-phenyl)-4-oxo-butyric acid ethyl ester 
• 99854-21-4 Methyl 4-(5-Chloro-2-hydroxyphenyl)-4-oxobutanoate 

Relevant articles and documents

Methods of using piperazine derivatives

The present invention relates to compounds of the formula I and the pharmaceutically acceptable forms thereof; wherein X, Y, a, b, c, d, R1, R2, R3, R4 and R5 are as defined herein. Moreover, the present invention is also directed at pharmaceutical compositions comprising a compound of the formula I and a pharmaceutically acceptable carrier. Furthermore, the present invention is directed at methods of using the herein described compounds and compositions for treating or preventing a disorder or condition that can be treated or prevented by antagonizing the CCR1 receptor in a mammal.

Photochemical Versus Aluminium Chloride-Catalyzed Fries Rearrangement of Aryl Hydrogen Succinates. Synthesis of 2(3H)-Furanones

The photochemical and aluminium chloride-catalyzed Fries rearrangement of a series of aryl hydrogen succinates 3 a-f to the corresponding 4-oxoacids 1 a-f are compared.Both approaches are complementary: the photochemical process is more general and becomes the method of choice for the succinoylation of phenols supporting alkoxy or hydroxy substituents, while the classical rearrangement is superior in the presence of alkyl or halogen substituents.These results are applied to the preparation of the 2(3H)-furanones 2 a-f. - Keywords: Fries rearrangement; Photo-Fries rearrangement; Aryl hydrogen succinates; 4-Oxoacids; 2(3H)-Furanones.

2-Aminomethyl-3,4-dihydronaphthalenes

Compounds of the formula STR1 and pharmaceutically acceptable salts thereof, wherein X and Y are independently H, F, Cl, Br, alkyl having up to four carbons, or alkoxy having up to four carbons, but X and Y are not both H, and Z is a secondary or tertiary amino group, are useful as analgesics and tranquillizing agents for mammals.