6291-06-1Relevant academic research and scientific papers
Genetic Encoding and Enzymatic Deprotection of a Latent Thiol Side Chain to Enable New Protein Bioconjugation Applications
Aust, Annika,Feldberg, Anna-Lena,Meyer-Ahrens, Pascal,Mootz, Henning D.,Reille-Seroussi, Marie
, p. 15972 - 15979 (2021)
The thiol group of the cysteine side chain is arguably the most versatile chemical handle in proteins. To expand the scope of established and commercially available thiol bioconjugation reagents, we genetically encoded a second such functional moiety in f
Light-Emitting Biomarker
-
, (2009/03/07)
The invention concerns novel 1,2-dioxetane derivatives of general formula (I) as defined in the description, capable of emitting a detectable luminescent signal, their use in a method for detecting and/or quantizing a physical, chemical or biological, in particular enzymatic, phenomenon, as well as a kit for implementing said method.
Solvent-free N-hydroxymethylation using formalin over basic alumina
Gupta, Rajive,Paul, Satya,Nanda, Puja
, p. 573 - 574 (2007/10/03)
A convenient and high yield method for N-hydroxymethylation of amines with formalin over basic alumina under solvent-free conditions with microwave heating is described.
S-Phenylacetamidomethyl (Phacm): an orthogonal cysteine protecting group for Boc and Fmoc solid-phase peptide synthesis strategies
Royo, Miriam,Alsina, Jordi,Giralt, Ernest,Slomcyznska, Urszula,Albericio, Fernando
, p. 1095 - 1102 (2007/10/02)
The reliability of the S-phenylacetamidomethyl-L-cysteine Cys(Phacm), a versatile derivative compatible with both Boc and Fmoc protection schemes, has been examined for solid-phase peptide synthesis.The Phacm group has the same properties as acetamidometh
