6291-06-1

Basic information

• Product Name: cyclobutylammonium chloride
• Synonyms: cyclobutylammonium chloride;N-Hydroxymethyl-2-phenylacetamide
• CAS NO: 6291-06-1
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 107.5819
• EINECS: 228-540-4
• Mol File: 6291-06-1.mol

Chemical Properties

• Melting Point: 78 °C
• Boiling Point: 398.1°C at 760 mmHg
• Flash Point: 194.6°C
• Appearance: /
• Density: 1.161g/cm³
• Vapor Pressure: 4.73E-07mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.34±0.10(Predicted)
• CAS DataBase Reference: cyclobutylammonium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: cyclobutylammonium chloride(6291-06-1)
• EPA Substance Registry System: cyclobutylammonium chloride(6291-06-1)

Safety Data

• Hazardous Substances Data: 6291-06-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Cyclobutylammonium chloride is utilized as a phase-transfer catalyst for enhancing the efficiency of organic synthesis reactions. Its ability to transfer ions across different phases makes it particularly useful in reactions involving the transfer of hydroxide ions, such as the Williamson ether synthesis and the Hofmann elimination.
Used in Pharmaceutical Synthesis:
As an important reagent in the field of organic chemistry, cyclobutylammonium chloride is employed in the synthesis of pharmaceuticals. Its role as a phase-transfer catalyst aids in the production of various medicinal compounds, contributing to the development of new drugs and therapies.
Used in Agrochemical Synthesis:
Cyclobutylammonium chloride also finds application in the synthesis of agrochemicals, where it serves as a phase-transfer catalyst to improve the efficiency of chemical reactions involved in the production of agricultural chemicals.
Used in Supramolecular Chemistry and Materials Science:
Due to its unique structural and chemical properties, cyclobutylammonium chloride has been studied for its potential use in supramolecular chemistry and materials science. This opens up possibilities for the development of new materials and applications based on its interaction with other molecules and compounds.

InChI:InChI=1/C9H11NO2/c11-7-10-9(12)6-8-4-2-1-3-5-8/h1-5,11H,6-7H2,(H,10,12)

Upstream product

• 103-81-1 Benzeneacetamide 
• 50-00-0 formaldehyd 

Downstream Products

• 1636-71-1 2-phenyl-N-piperidin-1-ylmethyl-acetamide 
• 102010-82-2 phenyl-acetic acid-{[(3,4-diethoxy-phenylsulfanyl)-methyl]-amide} 
• 412035-63-3 acetoxy-(2-phenyl-acetylamino)-methane 
• 24331-94-0 1,4-dihydro-3(2H)-isoquinolinone 
• 7500-45-0 N-benzylphenylacetamide 
• 340255-36-9 Methyl (4-[2-(acetyloxy)ethoxy]-5-methoxy-2-{[(phenylacetyl)amino]methyl}phenyl)acetate 
• 916220-28-5 methyl 4,5-dimethoxy-2-[(phenylacetamino)methyl]phenylacetate 

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