7500-45-0

Basic information

• Product Name: N-Benzylbenzeneacetamide
• Synonyms: N-Benzyl-2-phenylacetamide;N-Benzylbenzeneacetamide;N-Benzylphenylacetamide;BenzeneacetaMide, N-(phenylMethyl)-
• CAS NO: 7500-45-0
• Molecular Formula: C₁₅H₁₅NO
• Molecular Weight: 225.29
• Mol File: 7500-45-0.mol
• Article Data: 231

Chemical Properties

• Boiling Point: 446.9°C at 760 mmHg
• Flash Point: 268.9°C
• Appearance: /
• Density: 1.096g/cm³
• Vapor Pressure: 3.5E-08mmHg at 25°C
• Refractive Index: 1.581
• CAS DataBase Reference: N-Benzylbenzeneacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzylbenzeneacetamide(7500-45-0)
• EPA Substance Registry System: N-Benzylbenzeneacetamide(7500-45-0)

Safety Data

• Hazardous Substances Data: 7500-45-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 57, p. 6101, 1992 DOI: 10.1021/jo00049a009

InChI:InChI=1/C15H15NO/c17-15(11-13-7-3-1-4-8-13)16-12-14-9-5-2-6-10-14/h1-10H,11-12H2,(H,16,17)

Upstream product

• 100-39-0 benzyl bromide 
• 77287-34-4 formamide 
• 151-50-8 potassium cyanide 
• 100-44-7 benzyl chloride 
• 92-29-5 hydrobenzamide 
• 622-29-7 N-Benzylidenemethylamine 
• 101-97-3 Ethyl 2-phenylethanoate 
• 100-46-9 benzylamine 
• 103-82-2 phenylacetic acid 
• 103-80-0 phenylacetyl chloride 
• 101-41-7 benzeneacetic acid methyl ester 
• 937-39-3 2-phenylacetylhydrazine 
• 622-79-7 benzyl azide 
• 62901-67-1 N-Nitroso-N-benzylphenylacetamid 

Downstream Products

• 85909-01-9 Benzyl-phenylacetyl-carbamic acid tert-butyl ester 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 85-01-8 phenanthrene 
• 100-52-7 benzaldehyde 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 108-88-3 toluene 
• 100-46-9 benzylamine 
• 102-16-9 benzyl 2-phenylacetate 
• 101-97-3 Ethyl 2-phenylethanoate 
• 3583-52-6 C₁₅H₁₄ClN 
• 3647-71-0 N-benzyl-2-phenylethylamine 
• 132709-17-2 N-benzyl-2-phenylpropenamide 
• 34317-22-1 N-benzyl-N-methyl-2-phenylacetamide 
• 19857-42-2 2,3-dibenzylquinazolin-4(3H)-one 

Relevant articles and documents

Recyclization reactions of 1-alkylpyrimidinium salts

The reaction of 4-amino-2-benzyl-1-methyl-5-ethoxycarbonylpyrimidinium iodide ( 3 ) with alcoholic methylamine resulted in the formation of the methylimine of 2-amino-4- hydroxy-6-methylamino-5-phenylpyridine-3-carbaldehyde ( 5 ). Heating of the same pyri

Model experiments for peptide fragment coupling without racemization-prone activated amino acid derivatives.

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Method for preparing amide compounds through ionic liquid catalysis in high-pressure environment

The invention relates to a method for preparing amide compounds through ionic liquid catalysis in a high-pressure environment. According to the method, ionic liquid 1-ethyl-3-methylimidazolium acetateis used as a catalyst and a solvent, oxygen is used as an oxidizing agent, and aromatic methanol or alkyl alcohol is converted into an amide compound under the conditions of high pressure and heating. The synthesis method provided by the invention has the advantages that the raw material and technical cost is low; compared with other traditional methods, the method is safe, low in toxicity, economical and environmentally friendly; and the method has few steps, is simple and convenient to operate, is beneficial to large-scale synthesis, and has important significance for synthesis of amide compounds and large-scale industrialization of preparation.

Ammonia-borane as a Catalyst for the Direct Amidation of Carboxylic Acids

Ammonia-borane serves as an efficient substoichiometric (10%) precatalyst for the direct amidation of both aromatic and aliphatic carboxylic acids. In situ generation of amine-boranes precedes the amidation and, unlike the amidation with stoichiometric amine-boranes, this process is facile with 1 equiv of the acid. This methodology has high functional group tolerance and chromatography-free purification but is not amenable for esterification. The latter feature has been exploited to prepare hydroxyl- and thiol-containing amides.