62921-45-3

Basic information

• Product Name: 2H-Azirine-2-carboxaldehyde, 2-methyl-3-phenyl- (9CI)
• Synonyms: 2H-Azirine-2-carboxaldehyde, 2-methyl-3-phenyl- (9CI)
• CAS NO: 62921-45-3
• Molecular Formula: C₁₀H₉NO
• Molecular Weight: 159.18456
• Product Categories: ALDEHYDE
• Mol File: 62921-45-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2H-Azirine-2-carboxaldehyde, 2-methyl-3-phenyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Azirine-2-carboxaldehyde, 2-methyl-3-phenyl- (9CI)(62921-45-3)
• EPA Substance Registry System: 2H-Azirine-2-carboxaldehyde, 2-methyl-3-phenyl- (9CI)(62921-45-3)

Safety Data

• Hazardous Substances Data: 62921-45-3(Hazardous Substances Data)

Usage

Chemical compound

2H-Azirine-2-carboxaldehyde, 2-methyl-3-phenyl(9CI)

Properties

Highly reactive and unstable; contains a three-membered ring structure (aziridine)

Uses

Organic synthesis as a versatile intermediate for nitrogen-containing compounds; pharmaceutical and agrochemical industries for the synthesis of biologically active compounds

Caution

Handle with care due to reactivity and potential health hazards

Upstream product

• 173848-70-9 (Z)-3-bromo-2-methyl-3-phenylprop-2-en-1-al 
• 31357-81-0 (Z)-β-chloro-α-methyl-β-phenylacrolein 
• 35811-93-9 3-chloro-2-methylcinnamaldehyde 

Downstream Products

• 220478-03-5 C₂₈H₂₄NOP 
• 1008-28-2 5-methyl-4-phenyl-oxazole 
• 1433997-79-5 dimethyl 5-methyl-4-phenyl-2H-1,3-oxazine-2,2-dicarboxylate 
• 1607814-09-4 ethyl 2-cyano-5-methyl-4-phenyl-2H-1,3-oxazine-2-carboxylate 
• 1607814-22-1 ethyl 2-cyano-4-methyl-5-phenyl-3-oxo-2,3-dihydro-1H-pyrrole-2-carboxylate 
• 1607814-15-2 ethyl 5-methyl-4-phenyl-2-trifluoromethyl-2H-1,3-oxazine-2-carboxylate 

Relevant articles and documents

Carbene-Catalyzed [4 + 2] Annulation of 2 H-Azirine-2-carboxaldehydes with Ketones via Azolium Aza-Dienolate Intermediate

A new carbene-catalyzed [4 + 2] annulation of 2H-azirine-2-carbaldehydes with ketones was developed, thus providing the 2,3-dihydro-6H-1,3-oxazin-6-one core structures with broad scope and good to excellent yields. Notably, the azolium aza-dienolates gene

Novel pyridine-formation reactions of 2-(phosphoranylideneamino)acrylaldehydes with acetylenic esters. Synthesis of 2-mono-and 2,5-disubstituted nicotinates

Preparation of 2-(phosphoranylideneamino)acrylaldehydes, novel formyl-substituted (vinylimino)phosphoranes, was accomplished by the reaction of formyl-2H-azirines with triphenylphosphine. Their novel pyridine-formation reactions with acetylenic esters ach