62936-36-1

Usage

Uses

Used in Food and Beverage Industry:
ETHYL 4-ETHYLBENZOYLFORMATE is used as a flavoring agent to impart a sweet and fruity aroma to food and beverages, enhancing the sensory experience for consumers.
Used in Perfume Production:
ETHYL 4-ETHYLBENZOYLFORMATE is used as a fragrance component in the production of perfumes, contributing to the creation of complex and appealing scents.
Used in Cosmetics Industry:
In the cosmetics industry, ETHYL 4-ETHYLBENZOYLFORMATE is used as a scent component, adding a pleasant aroma to various cosmetic products.
Used in Pharmaceutical Synthesis:
ETHYL 4-ETHYLBENZOYLFORMATE is utilized in the synthesis of pharmaceuticals and pharmaceutical intermediates, playing a crucial role in the development of new medications.
It is important to handle ETHYL 4-ETHYLBENZOYLFORMATE with care, as it may cause irritation to the skin, eyes, and respiratory system. Proper safety measures and guidelines should be followed during its use.

InChI:InChI=1/C12H14O3/c1-3-9-5-7-10(8-6-9)11(13)12(14)15-4-2/h5-8H,3-4H2,1-2H3

Upstream product

• 6957-89-7 Ethyl dichloro-(ethoxy)-acetate 
• 71-43-2 benzene 
• 64-17-5 ethanol 
• 1345683-42-2 1-bromo-2-(4-ethylphenyl)acetylene 
• 100-41-4 ethylbenzene 
• 4755-77-5 Ethyl oxalyl chloride 

Downstream Products

• 83177-65-5 1-(4-ethylphenyl)-3-azabicyclo[3.1.0]hexane 
• 66504-45-8 1-(p-Ethylphenyl)-1,2-cyclopropan-dicarboximid 
• 77053-58-8 Brom-(4-ethyl-phenyl)-essigsaeure-ethylester 
• 77053-83-9 (1R,2S)-1-(4-Ethyl-phenyl)-cyclopropane-1,2-dicarboxylic acid 
• 77053-72-6 (1S,2R)-1-(4-Ethyl-phenyl)-cyclopropane-1,2-dicarboxylic acid diethyl ester 
• 1223562-83-1 (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (4-ethylphenyl)(oxo)acetate 
• 1544500-18-6 C₂₈H₃₁N₃O₃ 
• 107893-79-8 Cyclohexyl-(4-aethyl-phenyl)-glykolsaeure-(2-diaethylamino-aethylester)-methobromid 
• 4748-78-1 4-ethylbenzylaldehyde 
• 246161-07-9 N-(4-ethyl-benzylidene)-p-toluidine 
• 67302-72-1 (4-ethyl-benzyliden)-aniline 
• 10408-52-3 (rac)-2-(4-ethylphenyl)-2-hydroxyacetic acid 
• 14062-20-5 ethyl (4-ethyl-phenyl)-acetate 
• 94003-52-8 Cyclohexyl-(4-aethyl-phenyl)-glykolsaeure-aethylester 

Relevant academic research and scientific papers

Controllable chemoselectivity in the coupling of bromoalkynes with alcohols under visible-light irradiation without additives: Synthesis of propargyl alcohols and α-ketoesters

The chemoselectivity of visible-light-induced coupling reactions of bromoalkynes with alcohols can be controlled by simple changes to the reaction atmosphere (N2 or O2). A N2 atmosphere favours propargyl alcohols via a direct C-C coupling process, whereas an O2 atmosphere results in the generation of α-ketoesters through the oxidative CC/C-O coupling pathway.

Syntheses of Aryl Glyoxylate. I. The Reaction of Alkyl Dichloro(alkoxy)acetates with Aromatics in the Presence of Lewis Acid

Ethyl dichloro(ethoxy)acetate(1) and methyl dichloro(methoxy)acetate(2) were characterized.The reaction of 1 and 2 with aromatics in the presence of AlCl3 gave a considerable yield of aromatic α-keto ester.The aromatics included mono- and polymethylbenzene and anisol.The reaction was studied under various conditions and the results were compared with the acylation by ethoxalyl or methoxalyl chloride.The reaction mechanism was also discussed.

1-Aryl-3-azabicyclohexanes, a New Series of Nonnarcotic Analgesic Agents

A series of 1-aryl-3-azabicyclohexanes was synthesized by hydride reduction of 1-arylcyclopropanedicarboximides.Hydroxyphenyl analogues 20, 22, and 24 were prepared by EtSNa-DMF ether cleavage of the corresponding methoxyphenyl analogues 2m, 2n, and 23, respectively, with the secondary amines 20 and 22 going through the N-formyl intermediates 19 and 21.The p-ethoxy analogue 26 was obtained by O-ethylation of 19, followed by base hydrolysis of the amide 25.The greatest analgesic potency in mouse writhing and rat paw-pain assays was observed for para-substituted compounds.Bicifadine, 1-(4-methylphenyl)-3-azabicyclohexane (2b), was the most potent member of the series and is presently undergoing clinical trials in man.Analgesic activity of 2b is limited to the (+) enantiomer 2v, which has the 1R,5S absolute configuration as determined by single-crystal X-ray analysis.The N-methyl analogue (27d) of 2b showed significant analgesic potency, whereas the N-allyl (27a), N-(cyclopropylmethyl) (27b), and N-(n-hexyl) (27c) analogues were inactive.Bicifadine (2b) showed a nonnarcotic profile different from analogous azabicycloalkane and 3-phenylpyrrolidine analgesics.