10408-52-3

Usage

Uses

Used in Pharmaceutical Industry:
(4-ethylphenyl)(hydroxy)acetic acid is used as an active pharmaceutical ingredient for the development of drugs with anti-inflammatory and analgesic properties. Its ability to reduce inflammation and alleviate pain makes it useful in the treatment of various conditions.
Used as an Intermediate in Organic Synthesis:
(4-ethylphenyl)(hydroxy)acetic acid is used as an important intermediate in the synthesis of other organic compounds. Its unique structure and properties allow it to be a key component in the production of various chemical products.

Upstream product

• 134219-50-4 N-[2,2,2-Trichloro-1-(4-ethyl-phenyl)-ethyl]-benzamide 
• 937-30-4 4-ethylacetophenone 
• 7099-89-0 2-(4-ethylphenyl)-2-oxoacetic acid 
• 62936-36-1 ethyl 2-(4-ethylphenyl)-2-oxoacetate 
• 6316-07-0 N-(2,2,2-trichloro-1-hydroxyethyl)benzamide 
• 100-41-4 ethylbenzene 
• 609-09-6 Diethyl ketomalonate 

Downstream Products

• 14387-10-1 (4-ethyl-phenyl)-acetic acid 

Relevant academic research and scientific papers

Substituted amide phenol compound and its preparation method, pharmaceutical composition and use thereof

The invention discloses substituted-amide phenolic compounds, their preparation method, a pharmaceutical composition and an application thereof. The compounds have a structure as shown in the general formula I, wherein Z, L and Q are as defined in the spe

The Synthesis of Chiral α-Aryl α-Hydroxy Carboxylic Acids via RuPHOX-Ru Catalyzed Asymmetric Hydrogenation

A ruthenocenyl phosphino-oxazoline-ruthenium complex (RuPHOX?Ru) catalyzed asymmetric hydrogenation of α-aryl keto acids has been successfully developed, affording the corresponding chiral α-aryl α-hydroxy carboxylic acids in high yields and with up to 97% ee. The reaction could be performed on a gram scale with a relatively low catalyst loading (up to 5000 S/C) and the resulting products can be transformed to several chiral building blocks, biologically active compounds and chiral drugs. (Figure presented.).

N-(1-ARYL-2,2,2-TRIHALOGENOETHYL)CARBOXAMIDES

The readily obtained products from the condensation of trihalogenoacetaldehydes with carboxamides react with benzene and its homologs in the presence of concentrated sulfuric acid with the formation of N-(1-aryl-2,2,2-trihalogenoethyl)carboxamides.The latter were used for the production of 1-aryl-2,2,2-trihalogenoethylamines and 1-acylimino-1-aryl-2,2,2-trihalogenoethanes.