629624-19-7

Upstream product

• 10297-05-9 1-chloro 4-iodobutane 
• 98-81-7 1-bromovinylbenzene 
• 942-93-8 5-Chloro-1-phenyl-1-pentanone 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 126526-15-6 6-iodo-2-phenyl-1-hexene 
• 156419-13-5 4-Methyl-9-phenyl-9-decen-3-one 
• 156419-14-6 2-(5-Phenyl-5-hexanyl)cyclopentanone 
• 20049-04-1 (+)-(2S)-2-methyl-2-phenylcyclopentane 

Relevant academic research and scientific papers

Intramolecular carbolithiation promoted by a DTBB-catalysed chlorine-lithium exchange

The reaction of 6-chlorohex-1-ene 1 with lithium powder and a catalytic amount of 4,4′-di-tert-butylbiphenyl (DTBB, 5% molar) in THF at -78°C gives the corresponding organolithium intermediate 2, which by reaction with different electrophiles affords, aft

Synthesis of Substituted Cyclooctanols by a Samarium(II) Iodide Promoted 8-Endo Radical Cyclization Process

Samarium(II) iodide (SmI2) has been employed to promote an efficient 8-endo radical cyclization reaction of a variety of substituted olefinic ketones.Various substituted monocyclic, fused bicyclic, and bridged bicyclic cyclooctanols have been synthesized in fair to excellent yield via this protocol.In addition to delineating the synthetic potential of this reaction, experiments have been conducted to determine the source of reduced, noncyclized byproducts present in this and related SmI2-mediated reactions performed under protic conditions.