63-90-1

Usage

InChI:InChI=1/C9H13NO/c1-8(10-11)7-9-5-3-2-4-6-9/h2-6,8,10-11H,7H2,1H3

Upstream product

• 13213-36-0 1-phenylpropan-2-one oxime 
• 10048-64-3 (E)-1-phenylpropan-2-one oxime 
• 705-60-2 (2-nitroprop-1-enyl)benzene 
• 60-15-1 2-amino-1-phenylpropane 
• 705-60-2 1-phenyl-2-nitroprop-1-ene 
• 60-29-7 diethyl ether 
• 103-79-7 1-phenyl-acetone 

Downstream Products

• 58657-80-0 1-phenyl-2(α,α-azodioxy)-propane 
• 17322-34-8 (2-nitropropyl)benzene 
• 60-15-1 2-amino-1-phenylpropane 

Relevant academic research and scientific papers

N-oxygenation of amphetamine and methamphetamine by the human flavin- containing monooxygenase (form 3): Role in bioactivation and detoxication

(+)- And (-)-amphetamine and methamphetamine were N-oxygenated by the cDNA expressed adult human flavin-containing monooxygenase form 3 (FMO3), their corresponding hydroxylamines. Two major polymorphic forms of human FMO3 were studied, and the results sug

Action d'un Tetrafluoroborate d'Oxaziridinium sur les Amines et les Imines

The Oxaziridinium salt 1 derived from dihydroisoquinolin is an oxygen transfer reagent to primary amines leading to nitrosoderivatives (if R = Alkyl) or nitro compounds (if R = Aryl), to tertiary amines leading to N-oxides, and to secondary amines and imines leading to the corresponding nitrone.

Selected reductions of conjugated nitroalkenes

Conjugated nitroalkenes are readily reduced by a variety of borane and borohydride reagents. The reactions provide a convenient access to a number of nitrogen and oxygen based functional groups.

Identification of a nitrone as an in vitro metabolite of N-methylamphetamine

The relatively labile nitrone, α-methyl-(N-methylene)benzeneethanamine N-oxide was isolated from incubates of (±)-N-methylamphetamine with fortified liver homogenates from rats and rabbit. Identification of the nitrone was confirmed directly by gas chromatography and gas chromatography mass spectrometry and, after its conversion to isoxazolidine adducts by the action of methyl and ethyl acrylate. An authentic sample of the nitrone was synthesized unequivocally from N-hydroxyamphetamine and formaldehyde. The isomeric nitrone, N-(α-methylbenzeneethylidene)methylamine N-oxide, was also synthesized and its gas chromatographic and gas chromatographic mass spectrometric characteristics determined to confirm that the metabolically formed nitrone was not N-(α-methylbenzeneethylidene)methylamine N-oxide. Two previously unreported metabolites of (±)-N-methylamphetamine, N-hydroxyamphetamine and 1-hydroxy-1-phenyl-2-propanone, were isolated from rat in vitro experiments; the latter metabolite was not produced in vitro by rabbit liver homogenates.