17322-34-8

Basic information

• Product Name: 2-Nitro-1-phenylpropane
• Synonyms: 2-Nitro-1-phenylpropane;3-Phenyl-2-nitropropane
• CAS NO: 17322-34-8
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.19
• Mol File: 17322-34-8.mol
• Article Data: 54

Chemical Properties

• Boiling Point: 267.9°Cat760mmHg
• Flash Point: 117.4°C
• Appearance: /
• Density: 1.087g/cm³
• Vapor Pressure: 0.00791mmHg at 25°C
• Refractive Index: 1.523
• PKA: 7.96±0.13(Predicted)
• CAS DataBase Reference: 2-Nitro-1-phenylpropane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Nitro-1-phenylpropane(17322-34-8)
• EPA Substance Registry System: 2-Nitro-1-phenylpropane(17322-34-8)

Safety Data

• Hazardous Substances Data: 17322-34-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H11NO2/c1-8(10(11)12)7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3

Upstream product

• 705-60-2 (2-nitroprop-1-enyl)benzene 
• 705-60-2 1-phenyl-2-nitroprop-1-ene 
• 100-52-7 benzaldehyde 
• 79-24-3 Nitroethane 
• 14135-71-8 1-phenyl-2-propyl-4-toluenesulfonate 
• 13213-36-0 1-phenylpropan-2-one oxime 
• 100-51-6 benzyl alcohol 
• 60-29-7 diethyl ether 
• 29527-87-5 (2-iodopropyl)benzene 
• 2114-39-8 (2-bromopropyl)-benzene 
• 60-15-1 2-amino-1-phenylpropane 
• 58321-79-2 (Z)-(2-nitroprop-2-en-1-yl)benzene 
• 63-90-1 N-hydroxy-1-phenyl-2-propylamine 
• 83705-50-4 C₉H₁₀NO₂^(1-) 

Downstream Products

• 115412-38-9 4-(1-Methyl-1-nitro-2-phenyl-ethyl)-furan-2-carboxylic acid methyl ester 
• 102588-26-1 N-(3-phenylprop-1-en-2-yl)-O-(trimethylsilyl)-N-((trimethylsilyl)oxy)hydroxylamine 
• 57760-14-2 (S)-(-)-N-acetyl-α-methylphenylethylamine 
• 14383-60-9 (R)-(-)-N-acetyl-α-methylphenylethylamine 
• 51-64-9 dexamfetamine 
• 156-34-3 l-amphetamine 
• 1618669-10-5 C₂₈H₃₈ClN₃O₅ 
• 52271-37-1 N-Ethyl-N-(1-methyl-2-phenyl-ethyl)-hydroxylamine 
• 72687-64-0 N-ethyl-N-(1-phenylpropan-2-yl)acetamide 
• 457-87-4 N-ethylamphetamine 
• 859163-47-6 rac-N-4-nitrophenylsulfonyl-α-methylphenethylamine 
• 3121-50-4 (2-chloro-2-nitrosopropan-1-yl)benzene 

Relevant articles and documents

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THE NON-CHAIN RADICALOID C-ALKYLATION OF NITRONATE ANIONS: FURTHER EVIDENCE FOR THE MECHANISM

The effects of the variation of solvent, pyridinium leaving group, N-substituent, and nitronate nucleophile have been studied in the C-alkylation of nitronate anions.These variations and studies of the effects of inhibitors, attempted entrainment reactions, and ESR work are all in accord with our previously suggested mechanism.

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, and processes for making such modulators.

Iridium-catalyzed highly chemoselective and efficient reduction of nitroalkenes to nitroalkanes in water

An iridium-catalyzed highly chemoselective and efficient transfer hydrogenation reduction of structurally diverse nitroalkenes was realized at very low catalyst loading (S/C = up to 10000 or 20?000), using formic acid or sodium formate as a traceless hydride donor in water. Excellent functionality tolerance is also observed. The turnover number and turnover frequency of the catalyst reach as high as 18?600 and 19?200 h-1, respectively. An inert atmosphere protection is not required. The reactivities of nitroalkenes are dependent on their substitution pattern, and the pH value is a key factor to accomplish the complete conversion and excellent chemoselectivity. Purification of products is achieved by simple extraction without column chromatography. The reduction procedure is facilely amplified to 10 g scale at 10?000 S/C ratio. The potential of this green reduction in enantioselective hydrogenation has been demonstrated.

Nitroalkene reduction in deep eutectic solvents promoted by BH3NH3

Deep eutectic solvents (DESs) have gained attention as green and safe as well as economically and environmentally sustainable alternative to the traditional organic solvents. Here, we report the combination of an atom-economic, very convenient and inexpensive reagent, such as BH3NH3, with bio-based eutectic mixtures as biorenewable solvents in the synthesis of nitroalkanes, valuable precursors of amines. A variety of nitrostyrenes and alkyl-substituted nitroalkenes, including α- and β-substituted nitroolefins, were chemoselectively reduced to the nitroalkanes, with an atom economy-oriented, simple and convenient experimental procedure. A reliable and easily reproducible protocol to isolate the product without the use of any organic solvent was established, and the recyclability of the DES mixture was successfully investigated.