630103-34-3Relevant academic research and scientific papers
2-Substitution of Adenine Nucleotide Analogues containing a Bicyclo[3.1.0]hexane Ring System Locked in a Northern Conformation: Enhanced Potency as P2Y1 Receptor Antagonists
Kim, Hak Sung,Ohno, Michihiro,Xu, Bin,Kim, Hea Ok,Choi, Yongseok,Ji, Xiao D.,Maddileti, Savitri,Marquez, Victor E.,Harden, T. Kendall,Jacobson, Kenneth A.
, p. 4974 - 4987 (2007/10/03)
Preference for the northern (N) ring conformation of the ribose moiety of adenine nucleotide 3′,5′-bisphosphate antagonists of P2Y 1 receptors was established by using a ring-constrained methanocarba (a bicyclo[3.1.0]hexane) ring as a ribose su
