63019-68-1

Basic information

• Product Name: N-methyl-9H-fluoren-2-amine
• Synonyms: N-methyl-9H-fluoren-2-amine
• CAS NO: 63019-68-1
• Molecular Formula: C₁₄H₁₃N
• Molecular Weight: 195.28
• Mol File: 63019-68-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 78-78.5 °C(Solv: cyclopentane (287-92-3))
• Boiling Point: 321.94°C (rough estimate)
• Flash Point: 197.8°C
• Appearance: /
• Density: 1.0778 (rough estimate)
• Vapor Pressure: 7.73E-06mmHg at 25°C
• Refractive Index: 1.6353 (estimate)
• PKA: 4.88±0.20(Predicted)
• CAS DataBase Reference: N-methyl-9H-fluoren-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-9H-fluoren-2-amine(63019-68-1)
• EPA Substance Registry System: N-methyl-9H-fluoren-2-amine(63019-68-1)

Safety Data

• Hazardous Substances Data: 63019-68-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H13N/c1-15-12-6-7-14-11(9-12)8-10-4-2-3-5-13(10)14/h2-7,9,15H,8H2,1H3

Upstream product

• 67-56-1 methanol 
• 153-78-6 2-aminofluorene 
• 50-00-0 formaldehyd 
• 6633-48-3 1-Amino-2-dimethylamino-fluoren 
• 63019-66-9 indeno[2,1-c]-N-p-tosylanilide 
• 74-88-4 methyl iodide 
• 102479-05-0 N-fluoren-2-yl-N-methyl-toluene-4-sulfonamide 

Relevant articles and documents

Reusable Co-nanoparticles for general and selectiveN-alkylation of amines and ammonia with alcohols

A general cobalt-catalyzedN-alkylation of amines with alcohols by borrowing hydrogen methodology to prepare different kinds of amines is reported. The optimal catalyst for this transformation is prepared by pyrolysis of a specific templated material, which is generatedin situby mixing cobalt salts, nitrogen ligands and colloidal silica, and subsequent removal of silica. Applying this novel Co-nanoparticle-based material, >100 primary, secondary, and tertiary amines includingN-methylamines and selected drug molecules were conveniently prepared starting from inexpensive and easily accessible alcohols and amines or ammonia.

Room temperature N-heterocyclic carbene manganese catalyzed selective N-alkylation of anilines with alcohols

The first example of room temperature non-noble metal homogeneous system catalyzed selective N-alkylation of anilines with alcohols by a bis-NHC manganese complex is presented. This system was applied to a large range of alcohols and anilines, including biologically relevant motifs and challenging methanol. Experimental and computational studies suggest an outer-sphere mechanism for this NHC-Mn system.

Stereospecific copper-catalyzed domino ring opening and sp3 C-H functionalization of activated aziridines with N-alkylanilines

Copper efficiently catalyzed nucleophilic ring opening, sp3 C-H functionalization, and C-N bond formation in the presence of tert-butyl hydroperoxide to afford functionalized imidazolidines starting from N-sulfonylaziridines and Nalkylanilines. The products were obtained in high optical purities (95 → 99% ee) with excellent functional group tolerance.